Ectopic Pregnancy Biomarkers
| Status: | Completed |
|---|---|
| Conditions: | Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 8/17/2016 |
| Start Date: | June 2000 |
| End Date: | November 2013 |
Serum Bank for Assessment of Markers of Ectopic Pregnancy
In an attempt to simplify the diagnosis of ectopic pregnancy, the researchers will
investigate the presence of specific molecular markers of ectopic pregnancy. The
quantification of these (and other proteins) will be performed using the Ciphergen Protein
Chip system where serum is sampled with a high-throughput system. The patterns of these
peaks will be compared for those with a diagnosis of ectopic pregnancy and normal pregnancy.
Later goals of the research will be to identify the actual proteins that correspond to the
peaks which discriminate between the two clinical entitles. The goal is to identify a unique
protein pattern or protein peak to distinguish a normal intrauterine pregnancy from that of
an ectopic implanted gestation.
investigate the presence of specific molecular markers of ectopic pregnancy. The
quantification of these (and other proteins) will be performed using the Ciphergen Protein
Chip system where serum is sampled with a high-throughput system. The patterns of these
peaks will be compared for those with a diagnosis of ectopic pregnancy and normal pregnancy.
Later goals of the research will be to identify the actual proteins that correspond to the
peaks which discriminate between the two clinical entitles. The goal is to identify a unique
protein pattern or protein peak to distinguish a normal intrauterine pregnancy from that of
an ectopic implanted gestation.
Inclusion Criteria:
- Reproductive-aged women
- Currently pregnant based on serum human chorionic gonadotropin level
- Present for care for pregnancy due to vaginal bleeding and/or pelvic cramping
- Final diagnosis of one of the following:
1. Live intrauterine pregnancy through 14 weeks, diagnosed by ultrasound
demonstrating fetal heart motion
2. Diagnosed ectopic pregnancy
3. Ultrasound confirmation of a nonviable gestation (less 14 weeks) such as an
anembryonic gestation or a fetal demise
Exclusion Criteria:
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University of Miami A private research university with more than 15,000 students from around the...
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1240 North Mission Road # L919
Los Angeles, California 90033
Los Angeles, California 90033
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