Comparison of Transdermal and Oral Estrogens in Adolescent Girls With Ovarian Failure
| Status: | Archived |
|---|---|
| Conditions: | Women's Studies |
| Therapuetic Areas: | Reproductive |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | February 2007 |
| End Date: | February 2011 |
Comparison of Transdermal and Oral Estrogens in Adolescents With Ovarian Failure
To directly compare the safety (by laboratory evaluation) and efficacy (feminization and
growth) of three commonly used estrogen preparations in adolescent patients with ovarian
failure, either due to congenital causes (Turner syndrome) or medical therapies. We
hypothesize that transdermal estrogen will have equivalent efficacy and a more favorable
safety profile in comparison with conventional oral estrogen replacement.
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