Incidence and Relationship of Positive Preoperative Methicillin Resistant Staphylococcus Aureus (MRSA) Screens and Post-operative Infections
| Status: | Completed |
|---|---|
| Conditions: | Infectious Disease, Hospital |
| Therapuetic Areas: | Immunology / Infectious Diseases, Other |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 4/2/2016 |
| Start Date: | February 2008 |
| End Date: | May 2011 |
| Contact: | Cindy L. Hack, BSN |
| Email: | cynthia.hack@inova.org |
| Phone: | 703-858-8093 |
Evaluation of the Prevalence of Methicillin Resistant Staphylococcus Aureus Colonization in Pre-Surgical Patients and Post-Operative Infection
The purpose of this study is to evaluate the prevalence of pre-surgical patients who are
MRSA carriers. From an evidence-based practice perspective, findings from this study can be
considered in the evaluation of the hospital SOP mandating pre-surgical MRSA screening
requirements for patients with scheduled surgeries.
The central hypothesis to be addressed in this study is whether the MRSA colonization and
subsequent post-operative infection are the equivalent in these populations.
MRSA carriers. From an evidence-based practice perspective, findings from this study can be
considered in the evaluation of the hospital SOP mandating pre-surgical MRSA screening
requirements for patients with scheduled surgeries.
The central hypothesis to be addressed in this study is whether the MRSA colonization and
subsequent post-operative infection are the equivalent in these populations.
Design and Methods: Subjects in this study of 975 pre-operative, scheduled surgical patients
are in one of the three following groups:
- Group 1 (N=325): Allocation sample of surgical patients required to be MRSA screened
per hospital SOP (including patients having a positive MRSA history, orthopedic
surgery, undergoing dialysis, or transfer from another hospital, nursing home, skilled
nursing facility, or jail).
- Group 2 (N=650): Randomized sample (1:1 ratio) of surgical patients not required to be
MRSA screened per hospital SOP, to one of the following two groups:
- 2a (N=325): MRSA screening; or
- 2b (N=325): No MRSA screening. All subjects were followed for 30 days
post-operatively to determine the incidence of post-operative infection.
Treatment, diagnostic, and hospitalization data were collected for patients
diagnosed with post-operative infection.
are in one of the three following groups:
- Group 1 (N=325): Allocation sample of surgical patients required to be MRSA screened
per hospital SOP (including patients having a positive MRSA history, orthopedic
surgery, undergoing dialysis, or transfer from another hospital, nursing home, skilled
nursing facility, or jail).
- Group 2 (N=650): Randomized sample (1:1 ratio) of surgical patients not required to be
MRSA screened per hospital SOP, to one of the following two groups:
- 2a (N=325): MRSA screening; or
- 2b (N=325): No MRSA screening. All subjects were followed for 30 days
post-operatively to determine the incidence of post-operative infection.
Treatment, diagnostic, and hospitalization data were collected for patients
diagnosed with post-operative infection.
Inclusion Criteria:
1. Pre-surgical out patient at ILH
2. Surgical procedure scheduled at least 2 days before surgery
3. Surgery being done at ILH operating room
4. Provision of signed ICF
Exclusion Criteria:
1. Patient 18 years of age or older who is deemed by the hospital incapable of providing
Informed Consent
2. Inability to communicate in the English language
We found this trial at
2
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