Prevention of Infection in Surgical Treatment of Closed Fractures: Comparative of Cefazolin vs Vancomycin
| Status: | Completed |
|---|---|
| Conditions: | Orthopedic |
| Therapuetic Areas: | Orthopedics / Podiatry |
| Healthy: | No |
| Age Range: | 18 - 85 |
| Updated: | 1/1/2014 |
| Start Date: | February 2010 |
| End Date: | February 2013 |
| Contact: | Jeremy Bruce, M.D. |
| Email: | bruce_jeremy@hotmail.com |
| Phone: | 423-778-9202 |
Prevention of Infection in Surgical Treatment of Closed Fractures: A Comparative Study of Cefazolin Versus Vancomycin
With the growing incidence of MRSA in the hospital and community setting it would be
hypothesized that Vancomycin would decrease the risk of infection in patients requiring
surgical treatment of closed fracture as compared to Cefazolin.
hypothesized that Vancomycin would decrease the risk of infection in patients requiring
surgical treatment of closed fracture as compared to Cefazolin.
Inclusion Criteria:
Over 18 years of age or less than 85 years of age Ability to understand and agree to
informed consent Qualifying fracture requiring surgical intervention on one day.
Exclusion Criteria:
under 18 years of age or older than 85 years of age Unable to understand and agree to
informed consent Documented allergy to Cefazolin or Vancomycin Use of antibiotics within 2
weeks before or after injury Previous of MRSA infection Fractures requiring multiple
operations on various days Previous surgery on the injured extremity within 1 year
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