Laser Treatment for Fresh Surgical Scars and Mature Scars

Inclusion Criteria:

- Fitzpatrick Skin Type I-VI and either a fresh surgical scar (with sutures still
present [or dissolving sutures within 7 days of surgery for facial scars or within 14
days of surgery for scars on the trunk or extremities) of at least 2cm in length or an
erythematous and/or hypertrophic scar of at least 2cm in length and of greater than or
equal to 18 months in duration

- Scar is easily divisible into two equal segments for the purpose of the study, or is
bilateral in nature (e.g., inframammary)

Exclusion Criteria:

- Pregnant, lactating, or is planning to become pregnant

- history of cutaneous photosensitization, porphyria, hypersensitivity to porphyrins or
photodermatosis

- any skin pathology/condition that could interfere with evaluation or requires the use
of interfering topical systemic therapy

- coagulation disorder or currently using anti-coagulation medication (including but not
limited to heavy aspirin therapy)

- any condition which, in the investigator's opinion, would make it unsafe for the
subject to participate in the study

- currently enrolled in an investigational drug or device trial, or has received an
investigational drug or been treated with an investigational device within 30 days

- unable to communicate or cooperate with the investigator due to language problems,
poor mental development, or impaired cerebral function

- unreliable for the study, including subjects who engage in excessive alcohol intake or
drug abuse, or subjects who are unable to return for scheduled follow-up visits

- Isotretinoin therapy within 6 months

- need to be exposed to artificial tanning devices or excessive sunlight during the
trial

- prior treatment with parenteral gold therapy

- does not agree to refrain from other laser treatment, (micro)dermabrasion or topical
scar treatment creams for the duration of the study

- Diabetes Type 1 or 2

- Lupus, scleroderma or similar immune system disorder

- underlying silicone or other non-absorbable filler in the area of the scar

- phenol chemical peel or dermabrasion to the area of the scar within 3 months

- Fitzpatrick Skin Type IV, V or VI with a known sensitivity to hydroquinone or is
unwilling or unable to comply with physician/manufacturer instructions for the use of
this ingredient