Comparison of PEM Uptake Value (PUV) and Standardized Uptake Value (SUV) in Patients With Malignancies of the Breast
| Status: | Completed |
|---|---|
| Conditions: | Breast Cancer, Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | December 2009 |
| End Date: | November 2015 |
Pilot Study to Compare the PEM Uptake Value (PUV) and Standardized Uptake Value (SUV) in Patients With Malignancies of the Breast
The goal of this clinical research study is to learn if using the PEMFlex Solo II, a
high-resolution camera for positron emission tomography (PET) scan imaging, on an area of
the body that has, or is suspected to have cancer will give researchers the same or better
information about the disease compared to the images taken with a routine PET/computed
tomography (CT).
Researchers will compare the images taken using the PEMFlex Solo II to the images taken
during your scheduled routine PET/CT scan, as well as any additional routine CT scan(s),
magnetic resonance imaging (MRI) scan(s), and/or ultrasound image(s) you may have had within
the last 30 days or may have in the next 30 days.
high-resolution camera for positron emission tomography (PET) scan imaging, on an area of
the body that has, or is suspected to have cancer will give researchers the same or better
information about the disease compared to the images taken with a routine PET/computed
tomography (CT).
Researchers will compare the images taken using the PEMFlex Solo II to the images taken
during your scheduled routine PET/CT scan, as well as any additional routine CT scan(s),
magnetic resonance imaging (MRI) scan(s), and/or ultrasound image(s) you may have had within
the last 30 days or may have in the next 30 days.
If you agree to take part in this study, right after your already scheduled routine PET/CT
scan is complete, a study staff member will take you to a separate imaging room located in
the same clinic area where your routine PET/CT scan was just performed.
You will then sit in a chair as a study staff member positions the PEMFlex Solo II on either
side of your breast that has, or is suspected to have cancer. To take images using the
PEMFlex Solo II, the breast is placed between two flat panels on the scanning machine and
compressed (flattened). The position of the breast for this procedure is similar to getting
a mammogram, but the PEMFlex Solo II uses about 50% less force to compress the breast(s).
The compression will be repeated on the other breast if you are having scans of both breasts
performed.
It will take about 20 minutes to set up the PEMFlex Solo II and take the PET scan images.
Length of Study:
After the PET scan images have been taken using the PEMFlex Solo II, your participation in
this study will be over.
This is an investigational study. The PEMFlex Solo II is commercially available for PET scan
imaging of the breast.
Up to 24 patients will take part in this study. All will be enrolled at M. D. Anderson.
scan is complete, a study staff member will take you to a separate imaging room located in
the same clinic area where your routine PET/CT scan was just performed.
You will then sit in a chair as a study staff member positions the PEMFlex Solo II on either
side of your breast that has, or is suspected to have cancer. To take images using the
PEMFlex Solo II, the breast is placed between two flat panels on the scanning machine and
compressed (flattened). The position of the breast for this procedure is similar to getting
a mammogram, but the PEMFlex Solo II uses about 50% less force to compress the breast(s).
The compression will be repeated on the other breast if you are having scans of both breasts
performed.
It will take about 20 minutes to set up the PEMFlex Solo II and take the PET scan images.
Length of Study:
After the PET scan images have been taken using the PEMFlex Solo II, your participation in
this study will be over.
This is an investigational study. The PEMFlex Solo II is commercially available for PET scan
imaging of the breast.
Up to 24 patients will take part in this study. All will be enrolled at M. D. Anderson.
Inclusion Criteria:
1. A signed informed consent.
2. Known or suspected malignancy involving the breast as determined by biopsy, physical
examination or noninvasive imaging studies including plain films, CT, MR, ultrasound
or nuclear medicine imaging.
3. Scheduled for routine clinical imaging at the ACB PET/CT facility.
4. Participant must be at least 18 years of age.
Exclusion Criteria:
1. Uncontrolled blood glucose levels (>200 mg/dl).
2. Patient is unable to comprehend the requirements of the study.
3. Patient is unable to undergo scanning of the known or suspected lesion with the
high-resolution PEM (PET) scanner (due to body habitus, inability to comply with
positioning requirements, etc.).
We found this trial at
1
site
1515 Holcombe Blvd
Houston, Texas 77030
Houston, Texas 77030
713-792-2121
University of Texas M.D. Anderson Cancer Center The mission of The University of Texas MD...
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