Effect of Continuous Positive Airway Pressure (CPAP) and Cardiopulmonary Exercise Testing(CPET) in Patient With Obstructive Sleep Apnea (OSA) and Chronic Obstructive Pulmonary Disease (COPD)
Status: | Recruiting |
---|---|
Conditions: | Chronic Obstructive Pulmonary Disease, Insomnia Sleep Studies, Pulmonary |
Therapuetic Areas: | Psychiatry / Psychology, Pulmonary / Respiratory Diseases |
Healthy: | No |
Age Range: | 18 - Any |
Updated: | 5/5/2014 |
Start Date: | June 2009 |
End Date: | December 2016 |
Contact: | Gary Kinasewitz, MD |
Email: | gary-kinasewitz@ouhsc.edu |
Phone: | 405-271-6173 |
Effect of Nasal CPAP on Cardiopulmonary Exercise Testing in Patients With Overlap Syndrome
Nasal CPAP will improve cardiopulmonary exercise test (CPET) performance in patients with
overlap syndrome(COPD and OSA). Nasal CPAP is proven to improve cardiopulmonary exercise
testing in patients with OSA. The investigators hypothesis is that patients with overlap
syndrome will have a greater improvement in their cardiopulmonary exercise testing besides a
possible improvement in their lung function test and airway resistance.
overlap syndrome(COPD and OSA). Nasal CPAP is proven to improve cardiopulmonary exercise
testing in patients with OSA. The investigators hypothesis is that patients with overlap
syndrome will have a greater improvement in their cardiopulmonary exercise testing besides a
possible improvement in their lung function test and airway resistance.
Patients will be included if they have overlap syndrome. Patients will undergo a spirometry
and CPET before being started on CPAP. Those tests will be repeated after 8-12 weeks of CPAP
use. Patients will be excluded if they have any contraindication to mild exercise or they
can't perform an exercise test due to limited mobility.
and CPET before being started on CPAP. Those tests will be repeated after 8-12 weeks of CPAP
use. Patients will be excluded if they have any contraindication to mild exercise or they
can't perform an exercise test due to limited mobility.
Inclusion Criteria:
- Obstructive sleep apnea (OSA)
- COPD
Exclusion Criteria:
- Inability to perform exercise test due to musculoskeletal limitation
- Cardiac condition preventing patient from mild exercise
- Continuous oxygen supplement
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