Genetic Counseling and Lifestyle Change for Diabetes Prevention

This study will examine the impact diabetes genetic counseling on patient motivation and
disease prevention behaviors among subjects with pre-diabetes. We will randomize subjects
with pre-diabetes to genetic testing vs. no genetic testing in order to obtain an
unconfounded test of the hypothesis that genetic testing will change patient behavior.
Intervention subjects will be provided with their individual diabetes genotype risk score
derived from aggregating the combined results of 37 diabetes risk-associated genetic loci.
Because patients can receive either "Higher risk" or "Lower risk" genetic test results, we
will separately examine the impact of "Higher risk" and "Lower risk" test results compared
to untested controls. All subjects will be enrolled in a 12-week diabetes prevention
program.