Immune Response to the Human Papillomavirus Vaccine in Young Women With Inflammatory Bowel Disease



Status:Archived
Conditions:Cervical Cancer, Irritable Bowel Syndrome (IBS), Gastrointestinal
Therapuetic Areas:Gastroenterology, Oncology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:February 2010
End Date:February 2013

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Comparison of Immune Response to the Human Papillomavirus Vaccine in Young Women With and Without Inflammatory Bowel Disease


The Gardasil vaccine, a vaccine targeted towards the human papillomavirus (HPV), has been
shown to prevent the transmission of several strains of HPV in young women. Women with
inflammatory bowel disease (IBD) may not respond as well to this vaccine, either due to
having IBD or due to immunosuppressants used to control IBD. This study will test how well
women with IBD respond to the Gardasil vaccine.


Young women with inflammatory bowel disease who have not received the HPV vaccine will
receive the vaccine. The vaccine is given in 3 doses over 6 months. Response to the
vaccine will be measured 6 months after completing the vaccine series.


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200 First Street SW
Rochester, Minnesota 55905
507-284-2511
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