Pilot Study on the Tolerability of Dietary Dried Plum
Status: | Completed |
---|---|
Conditions: | Healthy Studies |
Therapuetic Areas: | Other |
Healthy: | No |
Age Range: | 50 - 75 |
Updated: | 10/28/2017 |
Start Date: | December 2009 |
Dried plums (Prunus domestica L.) have traditionally been recognized for their health
benefits related to conditions such as constipation, irregular menstrual cycles and mouth
sores. This dried fruit provides high levels of fiber, vitamins and minerals. Dried plum has
also been shown in animal studies to have beneficial effects on bone and can prevent the loss
of bone caused by low hormone levels such as occurs after surgical removal of the ovaries. We
also have shown that dried plum can prevent the loss of bone associated with aging in mice.
Very few therapies for osteoporosis actually reverse bone loss and improve bone strength. The
potential therapeutic value of dried plum in men and women with hormone deficiency or
age-related osteoporosis is clear.
benefits related to conditions such as constipation, irregular menstrual cycles and mouth
sores. This dried fruit provides high levels of fiber, vitamins and minerals. Dried plum has
also been shown in animal studies to have beneficial effects on bone and can prevent the loss
of bone caused by low hormone levels such as occurs after surgical removal of the ovaries. We
also have shown that dried plum can prevent the loss of bone associated with aging in mice.
Very few therapies for osteoporosis actually reverse bone loss and improve bone strength. The
potential therapeutic value of dried plum in men and women with hormone deficiency or
age-related osteoporosis is clear.
Inclusion Criteria:
- Age between 50 yrs and 75 yrs
- Nonsmokers
- Normal renal and hepatic function
Exclusion Criteria:
- Subjects who must follow a specific diet
- Subjects on any daily medications that affect bone health
- Subjects too heavy for the DEXA machine (weight limit 300 lbs)
- Subjects whose BMD by DEXA indicates osteoporosis
- Subjects unwilling to follow the diet specified
- Pregnant women
- Subjects who are unable to understand the consent form.
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