Herpes Simplex Type 2 Co-infection in Veterans With Chronic Hepatitis C
| Status: | Archived |
|---|---|
| Conditions: | Infectious Disease, Hepatitis |
| Therapuetic Areas: | Immunology / Infectious Diseases |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | April 2010 |
| End Date: | February 2011 |
The Interaction of HSV-2 Co-infection in Veterans With Chronic Hepatitis C: the Effect of Valacyclovir on HCV Viral Load
This trial is to determine the safety of valacyclovir in persons with chronic hepatitis C
and herpes simplex type 2 infection. Participants will be randomized to valacyclovir or
matching placebo. After receiving the initial therapy for eight weeks, the participants will
cross over to the alternate therapy for an additional eight weeks. Each treatment period
will be separated by a two-week period of daily placebo. The hypothesis is that treatment
with valacyclovir will result in a significant reduction in serum levels of hepatitis C
virus ribonucleic acid.
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