A Phase 1 Study of Brentuximab Vedotin Combined With ABVD for Hodgkin Lymphoma



Status:Archived
Conditions:Lymphoma
Therapuetic Areas:Oncology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:January 2010

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Trial Summary
Trial Overview
Inclusion Criteria

A Phase 1 Dose-Escalation Safety Study of Brentuximab Vedotin in Combination With ABVD as Frontline Therapy in Patients With Hodgkin Lymphoma


The purpose of this study is to assess the safety profile of brentuximab vedotin in
combination with ABVD in treatment-naive Stage IIa or IIb-IV Hodgkin lymphoma. It is a
phase 1, single-arm, open-label dose escalation study designed to define the MTD, PK,
immunogenicity and anti-tumor activity of brentuximab vedotin in combination with frontline
therapy.



We found this trial at
2
sites
University of Texas M.D. Anderson Cancer Center
1515 Holcombe Blvd
Houston, Texas 77030
 713-792-2121
University of Texas M.D. Anderson Cancer Center The mission of The University of Texas MD...
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Houston, TX
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Mayo Clinic Rochester
200 First Street SW
Rochester, Minnesota 55905
507-284-2511
Mayo Clinic Rochester Mayo Clinic is a nonprofit worldwide leader in medical care, research and...
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Rochester, MN
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