Safety and Dose Escalation Study of Zinc Supplementation in Critically Ill Children
| Status: | Completed |
|---|---|
| Conditions: | Hospital |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | Any - 10 |
| Updated: | 10/14/2017 |
| Start Date: | November 2008 |
| End Date: | November 2014 |
A Safety and Dose-escalation Study of Zinc Supplementation in Pediatric Critical Illness
The purpose of the study is 1) to determine whether administration of intravenous zinc to
critically ill children is safe, and 2) to determine an appropriate dose of zinc
supplementation.
critically ill children is safe, and 2) to determine an appropriate dose of zinc
supplementation.
Inclusion Criteria:
- Admission to pediatric intensive care unit
- Age between 1 month and 10 years
- Pediatric Risk of Mortality III score > 5, OR presence of at least 1 new organ failure
- Anticipated pediatric intensive care unit length of stay > 3 days
- Ability of parent or legal guardian to provide informed consent
Exclusion Criteria:
- Known zinc deficiency
- Pre-existing bone marrow failure
- New or existing diagnosis of diabetes mellitus
- Limitation of care orders in place
- New diagnosis of brain injury, encephalopathy
- Clinical contraindication for zinc supplementation
We found this trial at
1
site
747 52nd St
Oakland, California 94609
Oakland, California 94609
(510) 428-3000
Children's Hospital and Research Center Oakland For nearly 100 years, Children's Hospital & Research Center...
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