Dose-Ranging Study of Telintra® Tablets + Revlimid® in Patients With Non-Deletion (5q) Low to Intermediate-1 Risk Myelodysplastic Syndrome (MDS)



Status:Archived
Conditions:Cancer, Blood Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:November 2009
End Date:May 2012

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Trial Summary
Trial Overview
Inclusion Criteria

Phase 1 Dose-Ranging Study of Ezatiostat Hydrochloride (Telintra®, TLK199 Tablets)in Combination With Lenalidomide (Revlimid®)in Patients With Non-Deletion(5q) Low to Intermediate-1 Risk Myelodysplastic Syndrome (MDS)


This is an open label, multicenter Phase 1 dose escalation study evaluating five doses of
ezatiostat in combination with lenalidomide in patients with non-del(5q) low to intermediate
1 risk MDS. The HI-E, HI-N, HI-P rates [by International Working Group (IWG) 2006 criteria]
and safety of each treatment group will be evaluated to select the optimal dose of
ezatiostat in combination with lenalidomide for future studies.



We found this trial at
9
sites
Strong Memorial Hospital (University of Rochester School of Medicine)
601 Elmwood Ave
Rochester, New York 14642
(585) 275-2100
Strong Memorial Hospital (University of Rochester School of Medicine) In addition to offering traditional and...
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Rochester, NY
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Cleveland Clinic Florida
2950 Cleveland Clinic Blvd.
Weston, Florida 33331
866.293.7866
Cleveland Clinic Florida Cleveland Clinic Florida, located in Weston, West Palm Beach, Palm Beach Gardens...
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from
Weston, FL
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Center for Cancer & Blood Disorders
6410 Rockledge Dr #660
Bethesda, Maryland 20817
(301) 571-0019
Center for Cancer & Blood Disorders Widely recognized for its compassionate, expert care, the Center...
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from
Bethesda, MD
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Dana-Farber Cancer Institute
450 Brookline Ave
Boston, Massachusetts 2215
617-632-3000
Dana-Farber Cancer Institute Since it’s founding in 1947, Dana-Farber has been committed to providing adults...
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mi
from
Boston, MA
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University of Texas M.D. Anderson Cancer Center
1515 Holcombe Blvd
Houston, Texas 77030
 713-792-2121
University of Texas M.D. Anderson Cancer Center The mission of The University of Texas MD...
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from
Houston, TX
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Cardinal Bernardin Cancer Center at Loyola University Medical Center
2160 S. First Ave.
Maywood, Illinois 60153
888-584-7888
Cardinal Bernardin Cancer Center at Loyola University Medical Center The Cardinal Bernardin Cancer Center is...
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from
Maywood, IL
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Columbia Presbyterian Med Ctr
722 W 168th St
New York, New York 10032
(212) 305-2500
Columbia Presbyterian Med Ctr On January 1, 1998, The New York Hospital publicly announced its...
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mi
from
New York, NY
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Mayo Clinic Phoenix
Phoenix, Arizona 85054
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from
Phoenix, AZ
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Cancer Care Centers of South Texas
100 NE Loop 410; Suite 600
San Antonio, Texas 78216
210-424-1600
Cancer Care Centers of South Texas At Cancer Care Centers of South Texas, we are...
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mi
from
San Antonio, TX
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