Study Evaluating Long-Term Safety Of ATN-103 In Subjects With Rheumatoid Arthritis

Inclusion Criteria:

- Subjects must have completed study 3242K1-2000-WW or 3242K1-2001-JA and have had no
events that, in the opinion of the investigator, would preclude entry or
participation in this study.

Exclusion Criteria:

- Pregnant or nursing women.

- Any major illness/condition or evidence of an unstable clinical condition (eg, renal,
hepatic, cardiovascular, hematological, gastrointestinal, endocrine, pulmonary,
immunologic [eg, Felty syndrome, human immunodeficiency virus (HIV) infection],
infectious, neurological, or cerebral psychiatric disease, or evidence of
demyelinating disease) that, in the investigator's judgment, will substantially
increase the risk associated with the subject's developing an adverse event (AE) or
serious adverse event (SAE) during the study, or preclude the evaluation of the
subject's response.