A Study to Investigate the Use of Hydrogel Vehicle in Maintaining the Skin Barrier in Persons With Atopic Dermatitis
| Status: | Completed |
|---|---|
| Conditions: | Psoriasis, Dermatology |
| Therapuetic Areas: | Dermatology / Plastic Surgery |
| Healthy: | No |
| Age Range: | 12 - Any |
| Updated: | 3/30/2013 |
| Start Date: | February 2010 |
| End Date: | February 2011 |
| Contact: | Leon H. Kircik, M.D. |
| Email: | wedoderm@bellsouth.net |
| Phone: | 502-451-9000 |
Transepidermal Water Loss (TEWL) and Corneometry With Hydrogel Vehicle in the Treatment of Atopic Dermatitis - A Randomized, Investigator-Blind Pilot Study
While the repair of the epidermal barrier in atopic dermatitis is of major importance in the
treatment of atopic dermatitis, most of the vehicles used may actually cause a worsening of
an impaired epidermal barrier. Hydrogel vehicle is anecdotally known to be moisturizing and
hydrating.This study will compare the use of Hydrogel vehicle and Eucerin Lotion in
maintaining the epidermal barrier in subjects with atopic dermatitis.
Inclusion Criteria:
- Definitive diagnosis of atopic dermatitis as characterized by Hanifin and Rajka
criteria:
- 3 out of 4 major characteristics
- At least 3 minor characteristics
- Mild to moderate disease score of 2 or 3 by Investigator Global Assessment
- Minimum 5% Body Surface Area at Baseline
- Uniformly bilateral signs and symptoms of atopic dermatitis
- Able to understand and comply with the requirements of the study and sign Informed
Consent/HIPAA forms. Subjects under the legal age of consent must also have written
informed consent of the parent or legal guardian.
Exclusion Criteria:
- Allergy or sensitivity to any component of the test articles.
- Subjects who have not complied with the proper washout periods for prohibited
medications.
- Significant coagulation disorder or any medical condition that, in the opinion of the
investigator, contraindicates the subject's participation in the study.
- Recent alcohol or drug abuse is evident.
- History of poor cooperation, non-compliance with medical treatment or unreliability
- Participation in an investigational drug study within 30 days of the Baseline Visit.
We found this trial at
1
site
Click here to add this to my saved trials
