A Test of Nutritional Interventions to Enhance Weight Loss Maintenance
| Status: | Completed |
|---|---|
| Conditions: | Food Studies, Obesity Weight Loss |
| Therapuetic Areas: | Endocrinology, Pharmacology / Toxicology |
| Healthy: | No |
| Age Range: | 18 - 65 |
| Updated: | 10/11/2017 |
| Start Date: | October 2009 |
| End Date: | April 30, 2016 |
The purpose of this study is to compare standard Behavior Therapy (BT), BT plus Meal
Replacements (MR) and a condition focusing on the nutritional changes to the home food
environment (HFE) on weight loss, weight loss maintenance, nutritional composition of the
diet and psychosocial outcomes. A second aim is to determine the degree to which the specific
targets of the experimental interventions do in fact change in the anticipated direction
during the intervention and to evaluate whether such changes might account for improvements
in weight loss maintenance. This study is important because it could provide the first
evidence that the current standard of care for obesity lifestyle treatment could be improved
by the addition of MRs or a program of comprehensive nutritional change.
Replacements (MR) and a condition focusing on the nutritional changes to the home food
environment (HFE) on weight loss, weight loss maintenance, nutritional composition of the
diet and psychosocial outcomes. A second aim is to determine the degree to which the specific
targets of the experimental interventions do in fact change in the anticipated direction
during the intervention and to evaluate whether such changes might account for improvements
in weight loss maintenance. This study is important because it could provide the first
evidence that the current standard of care for obesity lifestyle treatment could be improved
by the addition of MRs or a program of comprehensive nutritional change.
Inclusion Criteria:
- Male and female participants between the ages of 18 and 65
- body mass index (BMI; kg/m2) between 27-45
- able to travel regularly to the study location
- interested in participating in a weight loss program.
Exclusion Criteria:
- currently enrolled in another organized weight loss program
- lactose intolerance
- taking medications that affect appetite (unless dosage had been stable for at least
the previous six months)
- history of gastric bypass or other surgical weight loss procedures
- medical conditions (e.g., cancer, substance abuse, psychotic disorders) that could
limit their ability to comply with the behavioral recommendations or pose a risk to
the participant during weight loss
- pregnancy or planning to become pregnant during the next two years -
- breastfeeding
- consuming an amount of alcohol that could interfere with study completion
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