Optimizing Hand Rehabilitation Post-Stroke Using Interactive Virtual Environments



Status:Completed
Conditions:Neurology
Therapuetic Areas:Neurology
Healthy:No
Age Range:18 - 80
Updated:4/21/2016
Start Date:March 2009
End Date:March 2015

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The complexity of sensorimotor control required for hand function as well as the wide range
of recovery of manipulative abilities makes rehabilitation of the hand most challenging. The
investigators past work has shown that training in a virtual environment (VE) using
repetitive, adaptive algorithms has the potential to be an effective rehabilitation medium
to facilitate motor recovery of hand function. These findings are in accordance with current
neuroscience literature in animals and motor control literature in humans. The investigators
are now in a position to refine and optimize elements of the training paradigms to enhance
neuroplasticity. The investigators first aim tests if and how competition among body parts
for neural representations stifles functional gains from different types of training
regimens. The second aim tests the functional benefits of unilateral versus bilateral
training regimens.The third aim tests whether functional improvements gained from training
in a virtual environment transfer to other (untrained) skills in the real world.

The complexity of sensorimotor control required for hand function as well as the wide range
of recovery of manipulative abilities makes rehabilitation of the hand most challenging. The
investigators past work has shown that training in a virtual environment (VE) using
repetitive, adaptive algorithms has the potential to be an effective rehabilitation medium
to facilitate motor recovery of hand function. These findings are in accordance with current
neuroscience literature in animals and motor control literature in humans. The investigators
are now in a position to refine and optimize elements of the training paradigms to enhance
neuroplasticity. The investigators first aim tests if and how competition among body parts
for neural representations stifles functional gains from different types of training
regimens. The second aim tests the functional benefits of unilateral versus bilateral
training regimens.The third aim tests whether functional improvements gained from training
in a virtual environment transfer to other (untrained) skills in the real world.

Inclusion Criteria:

- Six months post cerebrovascular accident

- Residual upper extremity impairment that affects participation

- At least ten degrees of active finger extension

- Tolerate passive shoulder flexion to chest level

Exclusion Criteria:

- Severe neglect

- Severe aphasia
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Newark, New Jersey 07102
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