Potassium-Magnesium Citrate as a Blood Pressure Lowering Agent in Hypertensive Patients
| Status: | Withdrawn |
|---|---|
| Conditions: | High Blood Pressure (Hypertension) |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 21 - 95 |
| Updated: | 2/13/2019 |
| Start Date: | September 2009 |
| End Date: | December 2012 |
Potassium-Magnesium Citrate as a Blood Pressure Lowering Agent in Hypertensive Patients; Role of Natriuresis
The goal of this study is to compare the effects of Potassium Magnesium Citrate to Potassium
Chloride on blood pressure among patients with pre-hypertension or mild hypertension. We will
also test whether Potassium Magnesium Citrate increases excretion of large amounts of sodium
in the urine.
Chloride on blood pressure among patients with pre-hypertension or mild hypertension. We will
also test whether Potassium Magnesium Citrate increases excretion of large amounts of sodium
in the urine.
Inclusion Criteria:
- Age greater than 21 years
- BMI > 18.5 kg/m2 and < 40 kg/m2
- Prehypertension and mild hypertension: BP systolic 120-159 mmHg, diastolic 80-95 mmHg
- Must agree to limit lifestyle changes including: 1) embarking on a new exercise or
weight reduction program 2) altering alcohol intake during the trial.
Exclusion Criteria:
- Taking blood pressure lowering medication
- Diabetes mellitus
- Renal disease
- Active cardiac disease
- Active liver disease
- Chronic diarrhea
- Chronic NSAID use
- Active or suspected drug use
- Uncontrolled psychiatric disease
- HIV infection
- Missed more than 20% of clinic visits in the last yr
- Prescription of diuretics for any reason
- A patient taking nutritional supplements including multivitamins that is unwilling to
discontinue them,\
- Consumption of greater than 14 alcoholic beverages per week
We found this trial at
2
sites
U.T. Southwestern Medical Center The story of UT Southwestern Medical Center is one of commitment...
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Dallas VA Medical Center VA North Texas Health Care System (VANTHCS) is a progressive health...
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