A Pilot Study of Vancomycin or Metronidazole in Patients With Primary Sclerosing Cholangitis
| Status: | Archived |
|---|---|
| Conditions: | Gastrointestinal |
| Therapuetic Areas: | Gastroenterology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | February 2010 |
| End Date: | February 2012 |
The purpose of this study is to determine whether Vancomycin or Metronidazole is safe and
beneficial in the treatment of Primary Sclerosing Cholangitis.
In this protocol, we propose the assessment of potential beneficial effects of the
antibiotics vancomycin and metronidazole on liver biochemistries, liver related symptoms and
Mayo risk score in patients with PSC. The patients will be randomized into four groups of
ten patients: one group will receive low dose vancomycin, one group will receive high dose
vancomycin, one group will receive low dose metronidazole and one group will receive high
dose metronidazole. Each group will be treated for three months.
We found this trial at
1
site
Mayo Clinic Rochester Mayo Clinic is a nonprofit worldwide leader in medical care, research and...
Click here to add this to my saved trials
