Rhythmic Auditory Stimulation and Walking Performance in Multiple Sclerosis (MS) Patients
| Status: | Archived |
|---|---|
| Conditions: | Neurology |
| Therapuetic Areas: | Neurology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | December 2010 |
| End Date: | February 2013 |
Rhythmic Auditory Stimulation and Walking Performance in MS Patients
The study is being conducted to determine if a home-based walking program that uses RAS
(Rhythmic Auditory Stimulation)is a viable and effective treatment of gait instability for
people with MS.We hypothesize that an RAS-based home walking program will demonstrate
significant improvements over both regular exercise and no exercise. To test this hypothesis
we will compare between group differences from baseline and three weeks of intervention on 3
quantitative gait measures and 1 standardized MS measurement from the following 3 groups:
RAS walking, RAS no walking Other: Walking exercise The secondary goal of the study will be
to determine any carry-over effects of RAS on gait parameters in ambulatory patients with
MS. We hypothesize that RAS will produce sustained changes in gait pattern due to
entrainment processes. To test this hypothesis, we will compare gait parameters two weeks
following the cessation of the intervention with baseline and with the last week of
intervention.
The third goal of this study is to determine if RAS-enhanced exercise has any transfer to
improve other areas such as upper extremity function and/or cognitive function. We
hypothesize that those participating in an RAS-based home walking program will demonstrate
improvements in other domain areas, such as cognitive and upper body functioning. To test
this hypothesis we will compare results from the Multiple Sclerosis Functional
Composite(MSFC) taken at baseline and again at the end of the treatment phase for all three
groups.
One hundred twenty nine patients will be recruited for the study.There will be three study
groups 1)the walking and music group,2)music only no walking group 3)walking only no music
group The subjects in the walking + music group and the music - no walking group will be
provided a list of songs to choose from. MP3 players will be provided that contain the
chosen music, which has been altered electronically with an embedded beat and set to their
baseline walking cadence +10%. The subjects in the walking + music group will be instructed
to walk while listening to the music for 20 minutes per day every day. The subjects in the
music - no walking group will be instructed to sit in a chair and listen to the music for 20
minutes per day every day. The subjects in the walking -no music group will be instructed
to walk for 20 minutes per day every day. The total duration of the interventions will be 3
weeks.
Study schedule Visit 1 (baseline): informed consent will be obtained. Subjects will be
screened for inclusion/exclusion criteria.Subjects qualified for the study will be
randomized to the treatment (MT) or control (C) group. Baseline assessments will be
performed on all subjects.Subjects in the walking+music group and the music- no walking
group will be given mp3 players with music.
Visit 2 (week 1): assessments will be performed on all subjects.
Visit 3 (week 2): assessments will be performed on all subjects.
Visit 4 (week 3): assessments will be performed on all subjects. All subjects will be
instructed to discontinue walking and music regimens.
Visit 5 (week 5): All subjects will return for final assessments.
We found this trial at
1
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Cleveland Clinic Florida Cleveland Clinic Florida, located in Weston, West Palm Beach, Palm Beach Gardens...
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