Determination of the in Vitro Effects of Cationic Airway Lining Modulators (CALM) on Chronic Obstructive Pulmonary Disease (COPD) Sputum



Status:Archived
Conditions:Chronic Obstructive Pulmonary Disease, Pulmonary
Therapuetic Areas:Pulmonary / Respiratory Diseases
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:April 2010
End Date:April 2011

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Determination of the in Vitro Effects of CALM on COPD Sputum


This study is intended to be an evaluation of the properties of human sputum collected from
patients with COPD. It is hypothesized that cationic airway lining modulators will have
beneficial effects on the rheological properties of sputum derived from patients with COPD.
Approximately 10 patients with COPD will collect sputum at home for 5 days. Samples will be
collected and tested in laboratory tests.



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