A Simplification Study of Unboosted Reyataz With Epzicom (ASSURE)

Status:	Archived
Conditions:	HIV / AIDS
Therapuetic Areas:	Immunology / Infectious Diseases
Healthy:	No
Age Range:	Any
Updated:	7/1/2011
Start Date:	April 2010
End Date:	August 2011

A Prospective, Randomized, Multicenter, Open-Label Study to Compare the Efficacy and Safety of Simplifying From a Regimen of Atazanavir (ATV) + Ritonavir (RTV) + Tenofovir/Emtricitabine to ATV + Abacavir/Lamivudine Without RTV in Virologically Suppressed, HIV-1 Infected, HLA-B*5701 Negative Subjects

This study is designed to compare the efficacy and safety of simplifying therapy from a
regimen of atazanavir (ATV) + ritonavir (RTV) + tenofovir/emtricitabine (TDF/FTC) to a
regimen of ATV + abacavir sulfate/lamivudine (ABC/3TC) without RTV in virologically
suppressed, HIV-1 infected, HLA-B*5701 negative subjects for 48 weeks.

A prospective, randomized, multicenter, open-label study to compare the efficacy and safety
of simplifying from a regimen of atazanavir (ATV) + ritonavir (RTV) +
tenofovir/emtricitabine (TDF/FTC) to ATV + abacavir sulfate/lamivudine (ABC/3TC) without RTV
for 48 weeks in virologically suppressed, HIV-1 infected, HLA-B*5701 negative subjects.

ViiV Healthcare is the new sponsor of this study, and GlaxoSmithKline is in the process of
updating systems to reflect the change in sponsorship.

We found this trial at

sites

Rhode Island Hospital

593 Eddy Street
Providence, Rhode Island 02903

401-444-4000