Study to Evaluate Subclinical Atherosclerosis (an Early Sign of Heart Disease) in Healthy Adult Immigrant Asian Indians
| Status: | Completed |
|---|---|
| Conditions: | Healthy Studies, Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Other |
| Healthy: | No |
| Age Range: | 20 - 65 |
| Updated: | 5/27/2013 |
| Start Date: | April 2010 |
| End Date: | April 2012 |
| Contact: | Rajiv Jauhar, MD |
| Email: | rjauhar@lij.edu |
| Phone: | 718-470-7340 |
Assessment of Subclinical Atherosclerosis in Healthy Adult Immigrant Asian Indians Using Flow Mediated Endothelial Dysfunction Method
Previous research has shown that Asian Indians are at relatively high risk for developing
diabetes, heart problems and high blood pressure.
The purpose of this study is to evaluate subclinical atherosclerosis (an early sign of heart
disease) which may be associated with abnormalities like diabetes mellitus, hypertension
(high blood pressure), high cholesterol and heart problems.
Endothelium is the inner lining of your blood vessels. Endothelial dysfunction is found more
in people with diabetes. In addition, high body mass index (BMI) is a strong risk factor for
developing metabolic abnormalities like diabetes mellitus. This research study may provide
information as to how useful endothelial dysfunction will be to detect people at risk of
metabolic abnormalities and heart disease at an early stage.
Two groups of subjects will be enrolled. Caucasians and Asian Indians There will be a total
of 100 subjects participating in this study. Approximately 50 Caucasians and 50 Asian
Indians will be enrolled. Caucasians will serve as the control group for this study.
Inclusion Criteria:
- Asian Indians and Caucasians between the ages of 20 and 65 living in the boroughs of
New York City and the Long Island area.
Subjects must provide a record of blood results completed within the past year to
determine eligibility (hematology and chemistry results).
Exclusion Criteria:
- Subjects with major underlying medical problems, including diabetes, hypertension,
coronary artery disease (CAD), hyperlipidemia, systolic blood pressure below 90 mm Hg
and liver or kidney disease will be excluded.
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Long Island Jewish Medical Center Serving North Shore LIJ Health System employees and their families....
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