An Active Approach to Treat Amblyopia: Perceptual Learning and Video Games
| Status: | Recruiting |
|---|---|
| Conditions: | Ocular |
| Therapuetic Areas: | Ophthalmology |
| Healthy: | No |
| Age Range: | 5 - 75 |
| Updated: | 11/1/2017 |
| Start Date: | July 2015 |
| End Date: | May 2020 |
| Contact: | Roger W Li, OD, PhD |
| Email: | oroger@berkeley.edu |
Improving Spatial and Temporal Vision in Adult and Juvenile Amblyopia
Amblyopia, a developmental abnormality that impairs spatial vision, is a major cause of
vision loss, resulting in reduced visual acuity and reduced sensitivity to contrast. This
study uses psychophysical measures to study neural plasticity in both adults and children
with amblyopia.
vision loss, resulting in reduced visual acuity and reduced sensitivity to contrast. This
study uses psychophysical measures to study neural plasticity in both adults and children
with amblyopia.
Amblyopia, a developmental abnormality that impairs spatial vision, is a major cause of
vision loss, resulting in reduced visual acuity and reduced sensitivity to contrast. Our
previous findings (see CITATIONS) show that the adult amblyopic brain is still plastic and
malleable, suggesting that active approach is potential useful in treating amblyopia. The
goal of this project is to assess the limits and mechanisms of neural plasticity in both
normal and amblyopic spatial vision. This study uses psychophysical measures to study neural
plasticity in both adults and children with amblyopia. Research participants will be asked to
practice a visual discrimination task (perceptual learning) or to play video games with the
amblyopic eye for a period of time. A range of visual functions will be monitored during the
course of treatment.
vision loss, resulting in reduced visual acuity and reduced sensitivity to contrast. Our
previous findings (see CITATIONS) show that the adult amblyopic brain is still plastic and
malleable, suggesting that active approach is potential useful in treating amblyopia. The
goal of this project is to assess the limits and mechanisms of neural plasticity in both
normal and amblyopic spatial vision. This study uses psychophysical measures to study neural
plasticity in both adults and children with amblyopia. Research participants will be asked to
practice a visual discrimination task (perceptual learning) or to play video games with the
amblyopic eye for a period of time. A range of visual functions will be monitored during the
course of treatment.
Inclusion Criteria:
- adults and children (>5 years old) with normal vision or amblyopia
- amblyopia: interocular VA difference of at least 0.1 logMAR
Exclusion Criteria:
- any ocular pathological conditions, nystagmus
We found this trial at
1
site
Berkeley, California 94720
Principal Investigator: Roger W Li, OD, PhD
Phone: 510-643-8685
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