Cell Culture of Glioma Specimens for in Vitro Preclinical Studies
| Status: | Completed |
|---|---|
| Conditions: | Brain Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/2/2016 |
| Start Date: | April 2009 |
| End Date: | June 2012 |
| Contact: | Yu-Hung Kuo, MD |
| Email: | kuoy@mail.amc.edu |
| Phone: | 518 262 5088 |
Primary Cell Culture of Surgical Glioma Specimens for Invitro Preclinical Studies
The purpose of this study is to culture primary human brain tumor cells with the specific
aims of:
1. Develop primary cultures from human brain tumor surgical specimens
2. Determine the genetic and molecular fingerprints of brain tumors that may have
prognostic significance
3. Delineate the mechanisms underlying oncogenesis of brain tumors.
4. Perform in vitro assays with brain tumor derived primary cultures to assess the
efficacy of novel therapeutic agents.
aims of:
1. Develop primary cultures from human brain tumor surgical specimens
2. Determine the genetic and molecular fingerprints of brain tumors that may have
prognostic significance
3. Delineate the mechanisms underlying oncogenesis of brain tumors.
4. Perform in vitro assays with brain tumor derived primary cultures to assess the
efficacy of novel therapeutic agents.
Inclusion Criteria:
- Patients 18 years of age or older undergoing surgical resection for glioma
Exclusion Criteria:
- Under 18 years of age
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