Validation of a Multi-gene Test for Lung Cancer Risk

Status:	Active, not recruiting
Conditions:	Lung Cancer, Cancer
Therapuetic Areas:	Oncology
Healthy:	No
Age Range:	50 - 90
Updated:	12/10/2017
Start Date:	May 2011
End Date:	September 2019

The purpose of this study is to determine the validity of a multi-gene Lung Cancer Risk Test
(LCRT). In the process, the investigators will establish a bank of NBEC samples and
corresponding blood samples from individuals demographically at increased risk for lung
cancer.

Because more than 160,000 individuals die of lung cancer/year in the United States alone, it
is important to use the best possible methods to determine whether increased surveillance of
individuals at highest risk for lung cancer will result in reduced lung cancer mortality. The
Lung Cancer Risk Test (LCRT) proposed for evaluation promises to accurately identify the
10-15% of the population that is most susceptible to lung cancer based on genetic
predisposition. More than 90 million individuals in the United States alone are
demographically at high risk for lung cancer and potential candidates for increased
surveillance.

Inclusion Criteria:

- 20 or more pack year smoking history

- clinical need for diagnostic bronchoscopy or consent to study driven bronchoscopy

Exclusion Criteria:

- Lung Cancer within 3 months after the date of enrollment

We found this trial at

sites

Medical University of South Carolina

171 Ashley Avenue
Charleston, South Carolina 29425

843-792-1414