Living Well With Stroke
| Status: | Completed |
|---|---|
| Conditions: | Depression, Neurology |
| Therapuetic Areas: | Neurology, Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 21 - Any |
| Updated: | 5/5/2014 |
| Start Date: | May 2010 |
| End Date: | June 2014 |
| Contact: | Catherine J Kirkness, PhD |
| Email: | kirkness@u.washington.edu |
| Phone: | 206 221-7971 |
Psychosocial/Behavioral Intervention in Post-Stroke Depression (PSD)
The overall goal of this study is to conduct a three-armed randomized controlled trial (RCT)
in stroke survivors with depression to determine if a brief psychosocial-behavioral therapy
intervention delivered in-person (arm A) or by telephone (arm B) is better than usual care
(arm C), in terms of percent reduction in depressive symptoms and % of participants
achieving remission of symptoms.
in stroke survivors with depression to determine if a brief psychosocial-behavioral therapy
intervention delivered in-person (arm A) or by telephone (arm B) is better than usual care
(arm C), in terms of percent reduction in depressive symptoms and % of participants
achieving remission of symptoms.
This is the second phase of a study whose aim was to evaluate the short and long-term
efficacy of a brief psychosocial/behavioral intervention (with adjunctive antidepressant)for
the treatment of post-stroke depression (PSD) in survivors of ischemic stroke (registered as
clinical trail NCT00194454). In the earlier trial we demonstrated that a pleasant
event/problem-solving brief psychosocial-behavioral therapy delivered by psychosocial nurse
practitioners was highly effective in treating major depression and promoting remission in
ischemic stroke survivors for up to two years. In this phase, we refine the protocol, and
potentially make it more cost effective, by conducting a randomized comparative
effectiveness trial of in-person versus telephone delivery of the intervention, comparing
with usual care control. We also seek to expand our sample to include hemorrhagic stroke
survivors (intraparenchymal hemorrhage and subarachnoid hemorrhage) as well as those with
ischemic stroke.
efficacy of a brief psychosocial/behavioral intervention (with adjunctive antidepressant)for
the treatment of post-stroke depression (PSD) in survivors of ischemic stroke (registered as
clinical trail NCT00194454). In the earlier trial we demonstrated that a pleasant
event/problem-solving brief psychosocial-behavioral therapy delivered by psychosocial nurse
practitioners was highly effective in treating major depression and promoting remission in
ischemic stroke survivors for up to two years. In this phase, we refine the protocol, and
potentially make it more cost effective, by conducting a randomized comparative
effectiveness trial of in-person versus telephone delivery of the intervention, comparing
with usual care control. We also seek to expand our sample to include hemorrhagic stroke
survivors (intraparenchymal hemorrhage and subarachnoid hemorrhage) as well as those with
ischemic stroke.
Inclusion Criteria:
- hospitalized for an ischemic or hemorrhagic stroke (intraparenchymal hemorrhage- IPH
or subarachnoid hemorrhage - SAH) in the past 3 months
- clinical depression symptoms (Geriatric Depression Score -GDS >= 11
Exclusion Criteria:
- major psychiatric co-morbidity
- active suicidal ideation without ability to contract for safety
- current substance abuse
- physical inability to tolerate 1-2 hour sessions
- receptive or global aphasia
- reduced level of consciousness (GCS<15).
We found this trial at
1
site
Univ of Washington Founded in 1861 by a private gift of 10 acres in what...
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