Low Field Magnetic Stimulation Treatment for Bipolar Depression



Status:Terminated
Conditions:Depression, Psychiatric, Bipolar Disorder
Therapuetic Areas:Psychiatry / Psychology
Healthy:No
Age Range:18 - 70
Updated:10/14/2017
Start Date:September 2004
End Date:January 2012

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Low Field Magnetic Stimulation in Bipolar Depression

Individuals with bipolar depression who had a particular kind of brain imaging reported
improved mood after the imaging. This effect may be linked to the changing magnetic fields
used during these magnetic resonance imaging studies. The current studies are designed to
further explore the important parameters of this effect and to clarify the degree and
duration of the mood effects.

An initial study using proton echo-planar magnetic resonance spectroscopic imaging (EP-MRSI)
in bipolar depressed individuals was associated with reports of improved mood. These studies
employed oscillating magnetic fields similar to those used in functional MRI (fMRI), but
which differ from the usual fMRI scan in field direction, waveform frequency, and strength.
As the abbreviation EP-MRSI is used to describe several relatively common MR sequences, the
specific potential clinical procedure being used is referred to as low field magnetic
stimulation or LFMS. Following these initial results, investigators are conducting studies to
determine the critical variables in both subjects and treatment for optimal response. Studies
are also underway to characterize the response of specific depression symptoms, the degree of
response, and the duration of response.

Inclusion Criteria:

- Primary diagnosis of bipolar disorder.

- Current depression.

Exclusion Criteria:

- Contraindication for MRI due to metal in eyes/head

- Claustrophobia.

- Inability to lie flat.

- History of brain injury.
We found this trial at
1
site
115 Mill St
Belmont, Massachusetts 02478
(617) 855-2000
McLean Hospital McLean Hospital is a comprehensive psychiatric hospital committed to providing easy access to...
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from
Belmont, MA
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