A Clinical Study of the Safety and Efficacy of MEBO Wound Ointment in Subjects With Venous Leg Ulcers

Status:	Completed
Conditions:	Other Indications, Cardiology, Gastrointestinal
Therapuetic Areas:	Cardiology / Vascular Diseases, Gastroenterology, Other
Healthy:	No
Age Range:	18 - Any
Updated:	1/12/2017
Start Date:	November 2010
End Date:	October 2011

A Phase II, Randomized, Controlled, Two-Center Pilot Study of the Safety and Efficacy of Topically Applied MEBO® Wound Ointment Compared to Standard of Care in Subjects With Venous Leg Ulcers

This is a Phase II, randomized, controlled, two-center pilot study designed to assess the
safety and efficacy of MEBO in the treatment of 14 subjects with VLUs. Subjects meeting
entry criteria will be randomly assigned in a 1:1 ratio for up to 8 weeks of treatment with
either MEBO or SOC (7 subjects per treatment arm).

Inclusion Criteria:

1. Male or female ≥18 years of age.

2. Able and willing to provide informed consent.

3. Able and willing to comply with protocol visits and procedures.

4. A full-thickness VLU that has been open continuously for ≥4 weeks and ≤1 year.

Exclusion Criteria:

1. Ulcer of a non-venous hypertensive pathophysiology.

2. Known or suspected allergy to any of the components of MEBO.

3. Malignancy on target ulcer limb.

4. Received another investigational device or drug within 30 days of enrollment.

5. Non-compliance in the screening or run-in period.

We found this trial at

sites

Center for Clinical Research

Castro Valley, California 94546

from

Castro Valley, CA