Sperm Banking Among Adolescents Newly Diagnosed With Cancer: Development of a Profiling and Referral Tool
| Status: | Completed |
|---|---|
| Conditions: | Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 13 - 21 |
| Updated: | 5/3/2014 |
| Start Date: | July 2010 |
| End Date: | June 2015 |
| Contact: | James Klosky, Ph.D |
| Email: | info@stjude.org |
| Phone: | 1-866-278-5833 |
Predictors of Adolescent Sperm Banking: Development of a Profiling and Referral Tool
Despite the known adverse effects of specific cancer treatments on fertility, only 18-26% of
at-risk adolescents and young men cryopreserve sperm prior to cancer treatment in the US:
These already less than optimal rates of sperm banking are even lower among adolescents who
have increased anxiety at cancer diagnosis, are lower in age and socioeconomic status, of
Evangelical religious orientation, or are diagnosed with leukemia/lymphoma: It is not clear
why sperm banking is underutilized, particularly in light of the high priority that
survivors of childhood cancer place on fertility and the high psychological distress
associated with fertility loss. Studies addressing sperm banking among adults with cancer
suggest that factors such as poor physician communication and the resulting lack of
fertility-risk knowledge by patients contributes to the low frequency of sperm
cryopreservation. No well-designed studies have examined risk factors associated with
failure to bank sperm among adolescents with cancer, a developmentally distinct population
ripe for intervention.
This study plans to enroll 206 adolescent males and 412 parents/guardians.
at-risk adolescents and young men cryopreserve sperm prior to cancer treatment in the US:
These already less than optimal rates of sperm banking are even lower among adolescents who
have increased anxiety at cancer diagnosis, are lower in age and socioeconomic status, of
Evangelical religious orientation, or are diagnosed with leukemia/lymphoma: It is not clear
why sperm banking is underutilized, particularly in light of the high priority that
survivors of childhood cancer place on fertility and the high psychological distress
associated with fertility loss. Studies addressing sperm banking among adults with cancer
suggest that factors such as poor physician communication and the resulting lack of
fertility-risk knowledge by patients contributes to the low frequency of sperm
cryopreservation. No well-designed studies have examined risk factors associated with
failure to bank sperm among adolescents with cancer, a developmentally distinct population
ripe for intervention.
This study plans to enroll 206 adolescent males and 412 parents/guardians.
This study will identify factors predictive of sperm banking/not sperm banking in order to
design interventions for increasing fertility preservation among adolescent males newly
diagnosed with cancer. Specifically, this study aims to investigate psychological,
demographic, developmental, parent/guardian, provider, and medical factors predictive of
sperm banking outcomes among at-risk adolescents with cancer. Once these factors have been
identified, the study will develop a novel Profiling and Referral Tool. This instrument
will ultimately serve as an intervention for both healthcare providers and families through
the facilitation of appropriate referrals, and tailored interventions for decreasing
barriers to sperm banking. Finally, the feasibility of the Profiling and Referral tool will
be evaluated based on provider and family report.
design interventions for increasing fertility preservation among adolescent males newly
diagnosed with cancer. Specifically, this study aims to investigate psychological,
demographic, developmental, parent/guardian, provider, and medical factors predictive of
sperm banking outcomes among at-risk adolescents with cancer. Once these factors have been
identified, the study will develop a novel Profiling and Referral Tool. This instrument
will ultimately serve as an intervention for both healthcare providers and families through
the facilitation of appropriate referrals, and tailored interventions for decreasing
barriers to sperm banking. Finally, the feasibility of the Profiling and Referral tool will
be evaluated based on provider and family report.
Inclusion Criteria:
- Male participants newly diagnosed with cancer.
- Patients must be between 13 years of age (≥ 13 years) and 21 years of age (< 22
years) at time of study enrollment.
- Participant Identified as Tanner stage III or higher.
- Participant identified by his oncologist (or designee) as being at risk for
treatment-related infertility.
- Proficiency speaking and reading English or Spanish.
- Cognitive capacity to complete study questionnaires.
Exclusion Criteria:
- Participant previously treated for cancer.
- History of mental retardation or severe cognitive or learning impairment.
We found this trial at
8
sites
St. Jude Children's Research Hospital St. Jude is unlike any other pediatric treatment and research...
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University of Michigan The University of Michigan was founded in 1817 as one of the...
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Children's Healthcare of Atlanta Whether treating a toddler in an emergency or supporting a teen...
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1500 East Duarte Road
Duarte, California 91010
Duarte, California 91010
626-256-HOPE (4673)
City of Hope National Medical Center City of Hope is dedicated to making a difference...
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