Mechanisms of Stroke in Intracranial Stenosis
| Status: | Archived |
|---|---|
| Conditions: | Neurology |
| Therapuetic Areas: | Neurology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | July 2010 |
The objective of this SAMMPRIS-affiliated study is to understand the mechanisms the
mechanisms that underlie ischemic stroke recurrence in high-grade intracranial
atherosclerotic disease in order to determine predictors of recurrent stroke. MoSIS will
evaluate 6 specific mechanisms of stroke in the medically-treated SAMMPRIS cohort: decreased
antegrade flow, progression of stenosis, decreased proximal collateral flow, decreased
distal collateral flow, impaired cerebrovascular reserve, and artery-to-artery embolism.
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