Galantamine in the Treatment of Post-Traumatic Headache



Status:Completed
Conditions:Cognitive Studies, Migraine Headaches, Hospital, Neurology, Urology
Therapuetic Areas:Nephrology / Urology, Neurology, Psychiatry / Psychology, Other
Healthy:No
Age Range:18 - 75
Updated:4/2/2016
Start Date:July 2005
End Date:August 2005
Contact:Lori L Flanagan, RN
Email:lc@nech.net
Phone:203-322-2748

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Trial Summary
Trial Overview
Inclusion Criteria

Galantamine in the Preventive Treatment of Chronic Post-Traumatic Headache

Most patients with CPTH present with additional major cognitive, behavioral and somatic
problems. Most drugs used currently have a negative influence on cognition. Therefore,
treatment strategies addressing both the headache and cognitive disturbances in patients
with CPTH are necessary. (CPTH; Chronic Post Traumatic Headache).

Headache is the most common symptom after a closed head injury, persisting for more then 2
months in 60% of the patients. CPTH is an important cause of consultations in neurology
offices and headache clinics, posing a severe burden and affecting the quality of life of
sufferers.

Inclusion Criteria:

Age range 18-75 CPTH according to ICHD-2 Fertile woman using adequate birth control
Willing and able to give informed consent Willing and able to complete the entire course
of the study to comply with study instructions Stable does of preventive medication

Exclusion Criteria:

Subject is pregnant or lactating Significant medical or psychiatric disease Previous
failure to 4 or more adequate trials of preventive medication Patient on non-stable dose
of medication used to prevent CPTH
We found this trial at
1
site
The New England Center for Headache
Stamford, Connecticut 06902
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mi
from
Stamford, CT
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