Safety and Tolerability of XmAb®5574 in Chronic Lymphocytic Leukemia



Status:Archived
Conditions:Blood Cancer, Lymphoma
Therapuetic Areas:Oncology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:September 2010
End Date:March 2012

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A Phase 1 Study of XmAb®5574 to Evaluate the Safety, Tolerability, and Pharmacokinetics in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia


This is an open-label, multi-dose, single-arm, Phase 1, dose-escalation study of XmAb5574.
The study will be conducted to identify the maximum tolerated dose (MTD) and/or recommended
dose(s) (RD) for further study, to characterize safety and tolerability, to characterize PK,
PD and immunogenicity, and to evaluate preliminary antitumor activity of XmAb5574 in
patients with relapsed or refractory CLL/SLL.



We found this trial at
2
sites
281 W. Lane Ave
Columbus, Ohio 43210
(614) 292-6446
Ohio State University The Ohio State University’s main Columbus campus is one of America’s largest...
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Columbus, OH
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230 25th Ave N
Nashville, Tennessee 37203
(615) 329-7274
Sarah Cannon Cancer Center People who live with cancer
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Nashville, TN
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