The Effect of Paricalcitol on Creatinine Filtration, Secretion and Glomerular Filtration Rate
| Status: | Archived |
|---|---|
| Conditions: | Renal Impairment / Chronic Kidney Disease |
| Therapuetic Areas: | Nephrology / Urology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | August 2010 |
| End Date: | June 2011 |
The purpose of this study is to study the effects of Paricalcitol (Zemplar) on kidney
functioning. The investigators hypothesize that the increase in serum creatinine observed
in recent paricalcitol trials is a function of reduced creatinine secretion and not an
actual reduction in kidney function. 16 patients will have kidney function measured via
iothalamate clearance at baseline, after 7 days of paricalcitol treatment and after 7 days
of being washed off the paricalcitol.
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