Efficacy and Safety of Sub-tenon Ranibizumab for Recurrent Pterygia



Status:Completed
Conditions:Ocular
Therapuetic Areas:Ophthalmology
Healthy:No
Age Range:18 - Any
Updated:4/2/2016
Start Date:August 2010
End Date:July 2012
Contact:Linda Rose, MD
Email:lirose@salud.unm.edu
Phone:505-272-6120

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The Use of Ranibizumab to Control Pterygium Growth in Recurrences and in Non-surgical Primary Lesions.

Ranibizumab, an effective antineovascular drug, will be studied for safety and efficacy in
pterygium, a neovascular disorder of the ocular surface.

Ptergyia are chronic fibrovascular lesions of the ocular surface. This study is designed to
look for a signal of efficacy when the lesions are in a phase of active vascular growth.
This phase is most often caught in a newly recurring pterygia post-operatively.

Patients identified with actively growing lesions, will be offered local injections directly
beneath the lesions. They will be examined for any adverse side effects and regression of
the lesion.

Inclusion Criteria:

Patients with actively growing pterygia, either surgical recurrences, or non-surgical
primary lesions.

Exclusion Criteria:

- Pregnancy

- History of CVA

- Monocular patients

- Minors
We found this trial at
1
site
Albuquerque, New Mexico 87131
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mi
from
Albuquerque, NM
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