Schizophrenia, Antipsychotic Treatment and the Risk for Diabetes Mellitus



Status:Completed
Conditions:Schizophrenia, Psychiatric, Diabetes
Therapuetic Areas:Endocrinology, Psychiatry / Psychology
Healthy:No
Age Range:14 - 50
Updated:4/2/2016
Start Date:August 2003
End Date:June 2014
Contact:Ripu D Jindal, MD
Email:jindalr@upmc.edu
Phone:412 512 9516

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This preliminary study aims to investigate the mechanism of higher rates of type 2 diabetes
mellitus in patients with schizophrenia. As part of the study, we collect
neuroendocrine-immune data on patients with first episode, treatment naive psychosis,
patients with newly diagnosed schizophrenia and normal healthy controls.

Regardless the treatment status, we collect the same neuroendocrine-immune data on the
participants after 2 months.

This preliminary study aims to investigate the mechanism of higher rates of type 2 diabetes
mellitus in patients with schizophrenia. As part of the study, we collect
neuroendocrine-immune data on patients with first episode, treatment naive psychosis,
patients with newly diagnosed schizophrenia and normal healthy controls.

Regardless the treatment status, we collect the same neuroendocrine-immune on the
participants (patients and controls) after 2 months. Thus, our study does not control
treatment. Patients take treatment in consultation with their physician. Some of them even
decide not to take any medications. At the 2nd visit, we do ask them about the the
medications they are taking if any.

Inclusion Criteria:

- Psychotic disorder as per DSM-IV criteria of the American Psychiatric Association

Exclusion Criteria:

- Diabetes, type 1 or 2

- Prominent substance abuse (i.e. psychotic symptoms attributable entirely to substance
use)

- Age above 50 or age below 14
We found this trial at
1
site
4200 Fifth Ave
Pittsburgh, Pennsylvania 15260
(412) 624-4141
University of Pittsburgh The University of Pittsburgh is a state-related research university, founded as the...
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