Examining Common Substrates of Eating and Alcohol Use Disorders
| Status: | Completed |
|---|---|
| Conditions: | Psychiatric |
| Therapuetic Areas: | Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 18 - 45 |
| Updated: | 5/5/2014 |
| Start Date: | July 2009 |
| End Date: | December 2013 |
| Contact: | Simona Kaplan, BA |
| Phone: | 212-543-5739 |
A substantial percentage of individuals with bulimia nervosa (BN) also meet criteria for a
co-occurring substance use disorder, such as alcohol abuse or dependence; however, research
examining this sub-group of patients with BN is limited. Understanding characteristics
common to both eating and alcohol use disorders may enhance understanding of the mechanisms
that could contribute to the co-occurrence and perpetuation of these disorders. Individuals
with BN and alcohol use disorders appear to share some behavioral traits, and therefore, the
primary aim of the current study is to compare patients with BN with and without an alcohol
use disorder and normal controls on measures assessing an individual's mood and ability to
perform certain tasks. Participants will be asked to complete computer-administered and
paper-and-pencil assessments and two laboratory test meals on separate days. By probing the
underpinnings of BN and alcohol use disorders, the investigators can determine whether these
disorders have a shared diathesis, which will lay an essential foundation for future
research to examine biological and genetic correlates of these disorders. Finally, as little
is known about the treatment of patients with BN and a co-occurring alcohol use disorder, an
exploratory aim of the current study is evaluate the suitability and efficacy of a
20-session cognitive-behavioral treatment (CBT) addressing both bulimic symptoms and alcohol
use.
co-occurring substance use disorder, such as alcohol abuse or dependence; however, research
examining this sub-group of patients with BN is limited. Understanding characteristics
common to both eating and alcohol use disorders may enhance understanding of the mechanisms
that could contribute to the co-occurrence and perpetuation of these disorders. Individuals
with BN and alcohol use disorders appear to share some behavioral traits, and therefore, the
primary aim of the current study is to compare patients with BN with and without an alcohol
use disorder and normal controls on measures assessing an individual's mood and ability to
perform certain tasks. Participants will be asked to complete computer-administered and
paper-and-pencil assessments and two laboratory test meals on separate days. By probing the
underpinnings of BN and alcohol use disorders, the investigators can determine whether these
disorders have a shared diathesis, which will lay an essential foundation for future
research to examine biological and genetic correlates of these disorders. Finally, as little
is known about the treatment of patients with BN and a co-occurring alcohol use disorder, an
exploratory aim of the current study is evaluate the suitability and efficacy of a
20-session cognitive-behavioral treatment (CBT) addressing both bulimic symptoms and alcohol
use.
A substantial percentage of individuals with bulimia nervosa (BN) also meet criteria for a
co-occurring substance use disorder, such as alcohol abuse or dependence; however, research
examining this sub-group of patients with BN is limited. Understanding characteristics
common to both eating and alcohol use disorders may enhance our understanding of the
mechanisms that could contribute to the co-occurrence and perpetuation of these disorders.
The primary aim of the current study is to compare patients with BN with and without an
alcohol use disorder and normal controls on computer-administered and paper-and-pencil
assessments and in two laboratory test meals (a binge meal and a normal meal) on separate
days. Participants will also complete self-report and interview measures of eating disorder
symptoms and alcohol consumption. By probing the underpinnings of BN and alcohol use
disorders, we can determine whether these disorders have a shared diathesis, which will lay
an essential foundation for future research to examine biological and genetic correlates of
these disorders. Finally, as little is known about the treatment of patients with BN and a
co occurring alcohol use disorder, an exploratory aim of the current study is to evaluate
the suitability and efficacy of a 20-session cognitive-behavioral treatment (CBT) addressing
both bulimic symptoms and alcohol use.
co-occurring substance use disorder, such as alcohol abuse or dependence; however, research
examining this sub-group of patients with BN is limited. Understanding characteristics
common to both eating and alcohol use disorders may enhance our understanding of the
mechanisms that could contribute to the co-occurrence and perpetuation of these disorders.
The primary aim of the current study is to compare patients with BN with and without an
alcohol use disorder and normal controls on computer-administered and paper-and-pencil
assessments and in two laboratory test meals (a binge meal and a normal meal) on separate
days. Participants will also complete self-report and interview measures of eating disorder
symptoms and alcohol consumption. By probing the underpinnings of BN and alcohol use
disorders, we can determine whether these disorders have a shared diathesis, which will lay
an essential foundation for future research to examine biological and genetic correlates of
these disorders. Finally, as little is known about the treatment of patients with BN and a
co occurring alcohol use disorder, an exploratory aim of the current study is to evaluate
the suitability and efficacy of a 20-session cognitive-behavioral treatment (CBT) addressing
both bulimic symptoms and alcohol use.
Inclusion Criteria:
- Age 18-45
- Diagnosis of bulimia nervosa with or without a co-occurring alcohol use disorder
- English speaking
- Weight above 80% of ideal
Exclusion Criteria:
- Other significant psychiatric conditions requiring treatment or a significant medical
condition
- Pregnancy
- Current use of psychotropic medication
- History of neurological disorder (e.g., dementia, stroke seizure)
- Food allergy to items in the lunch buffet
- Positive urine drug screen
- Current or post eating disorder diagnosis or history of binge eating or vomiting
- Current or past alcohol or substance abuse or dependence
We found this trial at
2
sites
New York State Psychiatric Institute The New York State Psychiatric Institute (NYSPI), established in 1895,...
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New York State Psychiatric Institute The New York State Psychiatric Institute (NYSPI), established in 1895,...
Click here to add this to my saved trials