Collection of Blood and/or Bone Marrow for Investigation and Characterization of Normal and Abnormal Cell Growth



Status:Recruiting
Conditions:Blood Cancer, Leukemia
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:4/17/2018
Start Date:September 2009
End Date:December 2100
Contact:Jan Cerny, MD, PhD
Email:Jan.Cerny@umassmemorial.org
Phone:774-442-3903

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Collection of Blood and/or Bone Marrow for Investigation and Characterization of Normal and Abnormal Cell Growth in Patients With Malignancy or Hematologic Disorders

The collection of Blood and/or Bone Marrow from patients with blood disorders, blood cell
malignancies and associated conditions will serve as a convenient and comprehensive source of
tissue to give us further information about the differences between normal blood cells and
blood cells of affected individuals. This will be an invaluable asset for understanding the
biology of blood disorders. The collected samples will be used by investigators for studies
including immunology, molecular biology and genetics to name a few.


Inclusion Criteria:

- Selected patients over the age of 18 with hematologic malignancies or other blood
disorders (leukemia, myeloproliferative disorders, lymphoma, other malignancies
involving the bone marrow or patients with unexplained alterations in their complete
blood count).

Patients who are scheduled to undergo a bone marrow aspirate and/or phlebotomy for other
clinical indications will be asked to participate. They will be asked to donate an
additional small aliquot of bone marrow and/or blood during the course of their already
scheduled bone marrow aspiration or phlebotomy.

Exclusion Criteria:

- Patients with pre-existing medical conditions that might be exacerbated by the
procedure of obtaining bone marrow or blood

- Patients who are allergic to Lidocaine, which is used as a local anesthetic, and who
cannot receive a suitable substitute anesthetic.

- Patients who have a bleeding diathesis which might pose a problem with marrow
aspiration.

- Patients unable to give informed consent.

- Pregnant patients
We found this trial at
1
site
55 N Lake Ave
Worcester, Massachusetts 01655
(508) 856-8989
Principal Investigator: Jan Cerny, MD, PhD
Phone: 774-442-3903
Univ of Massachusetts Med School As the commonwealth's only public medical school, we take seriously...
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