An Inpatient Study Of The Efficacy, Safety, And Tolerability Of PF-02545920 In The Treatment Of Acute Exacerbation Of Schizophrenia
Status: | Completed |
---|---|
Conditions: | Schizophrenia |
Therapuetic Areas: | Psychiatry / Psychology |
Healthy: | No |
Age Range: | 18 - 65 |
Updated: | 5/24/2018 |
Start Date: | October 2010 |
End Date: | August 2011 |
A Phase 2, Multicenter, Double-blind, Randomized, Parallel Group, 4-week Inpatient Study To Evaluate The Safety And Efficacy Of Two Fixed Doses Of Pf-02545920 Compared To Placebo In The Treatment Of Acute Exacerbation Of Schizophrenia Using Risperidone As An Active Control
This study aims to evaluate whether PF-02545920 is safe and effective in the treatment of
acute exacerbation of schizophrenia during a 4-week inpatient treatment period. The study
will use the Positive and Negative Syndrome Scale (PANSS) to measure change in symptoms for
PF-02545920 compared to risperidone and placebo treatment.
acute exacerbation of schizophrenia during a 4-week inpatient treatment period. The study
will use the Positive and Negative Syndrome Scale (PANSS) to measure change in symptoms for
PF-02545920 compared to risperidone and placebo treatment.
Inclusion Criteria:
- Diagnosis of schizophrenia with acute exacerbation of illness
- The current acute exacerbation of schizophrenia must be less than 4 weeks duration
prior to the initial evaluation.
Exclusion Criteria:
- Subjects with evidence or history of clinically significant uncontrolled medical
illness
- Subjects with a current diagnosis of schizoaffective disorder, major depression,
bipolar disorder, or obsessive compulsive disorder.
- Subjects who meet Diagnostic and Statistical Manual-IV (DSM-IV)defined diagnostic
criteria for psychoactive substance dependence (excluding nicotine dependence) within
12 months of screening or DSM-IV defined substance abuse within 3 months prior to
screening.
We found this trial at
39
sites
8043 Cooper Creek Boulevard
Suite 107
Bradenton, Florida 34201
Bradenton, Florida 34201
(941) 747-7900
Florida Clinical Research Center, LLC Led by Andrew J. Cutler, M.D., Florida Clinical Research Center,...
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Atlanta Center for Medical Research Welcome to the Atlanta Center for Medical Research, a leader...
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101 The City Drive South
Orange, California 92868
Orange, California 92868
714-456-7890
University of California, Irvine Medical Center We are UC Irvine Health. We are a devoted...
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