Stress, Hormones, and Eating
Status: | Archived |
---|---|
Conditions: | Food Studies, Psychiatric |
Therapuetic Areas: | Pharmacology / Toxicology, Psychiatry / Psychology |
Healthy: | No |
Age Range: | Any |
Updated: | 7/1/2011 |
Start Date: | July 2010 |
End Date: | December 2011 |
Novel Interventions to Reduce Stress Induced Non-homeostatic Eating
The investigators will develop a measure of endogenous opioid tone that might serve as a
biological marker for drive for palatable food. Using a 'naltrexone probe,' the
investigators will assess whether individual response to one dose of an opioid receptor
antagonist, naltrexone, is related to non-homeostatic eating in non-pregnant women.
Hypothesis 1: Naltrexone Response will be related to non-homeostatic eating.
Hypothesis 2: Response profiles to the 25 mg dose will be slightly less in magnitude than
the 50 mg dose. However, responses will be similarly related to non-homeostatic eating
measures.
Hypothesis 3: Response to naltrexone will be highly stable within individuals across time,
in the absence of an intervention.
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