Sanctura Muscarinic Receptor Antagonist Resists Transport (SMART-II) Trial
| Status: | Completed |
|---|---|
| Conditions: | Overactive Bladder |
| Therapuetic Areas: | Gastroenterology |
| Healthy: | No |
| Age Range: | 60 - Any |
| Updated: | 4/21/2016 |
| Start Date: | August 2010 |
| End Date: | March 2011 |
This study will evaluate the cerebrospinal fluid levels of trospium chloride (Sanctura XR®)
and oxybutynin immediate release (Oxybutynin IR) on memory performance in patients with
overactive bladder and age associated memory impairment.
and oxybutynin immediate release (Oxybutynin IR) on memory performance in patients with
overactive bladder and age associated memory impairment.
Inclusion Criteria:
- Patient presents symptoms of overactive bladder
- Patient has age associated memory impairment
- No acute or unstable medical conditions
Exclusion Criteria:
- History of alcohol or substance abuse within 1 year prior to study
- Has donated in excess of 500mL of blood or plasma in the 30 days prior to study
- Has known bleeding disorder (hemophilia)
- Previous abdominal bypass surgery for obesity
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