Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results
Status: | Completed |
---|---|
Conditions: | Diabetes |
Therapuetic Areas: | Endocrinology |
Healthy: | No |
Age Range: | 50 - Any |
Updated: | 1/3/2019 |
Start Date: | August 31, 2010 |
End Date: | December 17, 2015 |
A Long-term, Multi-centre, International, Randomised Double-blind, Placebo-controlled Trial to Determine Liraglutide Effects on Cardiovascular Events
This trial is conducted in Africa, Asia, Europe, and North and South America. The aim of this
trial is to determine the long term effect of liraglutide on cardiovascular events in
subjects with type 2 diabetes.
trial is to determine the long term effect of liraglutide on cardiovascular events in
subjects with type 2 diabetes.
Inclusion Criteria: - Type 2 diabetes - Age min. 50 years at screening and concomitant
cardiovascular, cerebrovascular or peripheral vascular disease or chronic renal failure or
chronic heart failure OR age min. 60 years at screening and other specified risk factors of
cardiovascular disease - HbA1c: 7.0% or above - Anti-diabetic drug naive or treated with
one or more oral anti-diabetic drugs (OADs) or treated with human NPH insulin or
long-acting insulin analogue or premixed insulin, alone or in combination with OAD(s)
Exclusion Criteria: - Type 1 diabetes - Use of a glucagon-like peptide-1 (GLP-1) receptor
agonist (exenatide, liraglutide or other) or pramlintide or any dipeptidyl peptidase 4
(DPP-4) inhibitor within the 3 months prior to screening (trial start) - Use of insulin
other than human NPH insulin or long-acting insulin analogue or premixed insulin within 3
months prior to screening. Short-term use of other insulin during this period in connection
with intercurrent illness is allowed, at Investigator's discretion
We found this trial at
110
sites
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