Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results



Status:Completed
Conditions:Diabetes
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:50 - Any
Updated:1/3/2019
Start Date:August 31, 2010
End Date:December 17, 2015

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A Long-term, Multi-centre, International, Randomised Double-blind, Placebo-controlled Trial to Determine Liraglutide Effects on Cardiovascular Events

This trial is conducted in Africa, Asia, Europe, and North and South America. The aim of this
trial is to determine the long term effect of liraglutide on cardiovascular events in
subjects with type 2 diabetes.


Inclusion Criteria: - Type 2 diabetes - Age min. 50 years at screening and concomitant
cardiovascular, cerebrovascular or peripheral vascular disease or chronic renal failure or
chronic heart failure OR age min. 60 years at screening and other specified risk factors of
cardiovascular disease - HbA1c: 7.0% or above - Anti-diabetic drug naive or treated with
one or more oral anti-diabetic drugs (OADs) or treated with human NPH insulin or
long-acting insulin analogue or premixed insulin, alone or in combination with OAD(s)
Exclusion Criteria: - Type 1 diabetes - Use of a glucagon-like peptide-1 (GLP-1) receptor
agonist (exenatide, liraglutide or other) or pramlintide or any dipeptidyl peptidase 4
(DPP-4) inhibitor within the 3 months prior to screening (trial start) - Use of insulin
other than human NPH insulin or long-acting insulin analogue or premixed insulin within 3
months prior to screening. Short-term use of other insulin during this period in connection
with intercurrent illness is allowed, at Investigator's discretion
We found this trial at
110
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Escondido, California 92025
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Alabaster, Alabama 35007
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Albany, New York 12208
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Anaheim, California 92801
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Arlington, Texas 76012
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Asheville, North Carolina 28801
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Aurora, Colorado 80010
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Baltimore, Maryland 21229
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Bartlett, Tennessee 38133
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Beaver, Pennsylvania 15009
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Birmingham, Alabama 35215
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Blacktown, New South Wales
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Bloomfield Hills, Michigan 48302
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Bradenton, Florida 34201
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Buffalo, New York 14222
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Burlington, North Carolina 27215
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Cerritos, California 90703
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Chapel Hill, North Carolina 27599
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Charleston, South Carolina 29407
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Chicago, Illinois 60612
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Cincinnati, Ohio 45229
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Clearwater, Florida 33756
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Columbia, South Carolina 29203
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Corpus Christi, Texas 78404
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Crystal Lake, Illinois 60012
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Dearborn, Michigan 48124
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Fort Lauderdale, Florida 33316
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Fresno, California 93702
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Greensboro, North Carolina 27408
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Greenville, North Carolina 27834
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Hatfield, Pennsylvania 19440
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Houston, Texas 77030
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Interlochen, Michigan 49643
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Longview, Texas 75605
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Los Banos, California 93635
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Lubbock, Texas 79423
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Mooresville, North Carolina 28117
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Murrells Inlet, South Carolina 29576
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Myrtle Beach, South Carolina 29572
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Nashua, New Hampshire 03063
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Philadelphia, Pennsylvania 19104
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