Conversion to Embeda With Rescue Trial



Status:Terminated
Conditions:Chronic Pain
Therapuetic Areas:Musculoskeletal
Healthy:No
Age Range:21 - Any
Updated:10/14/2017
Start Date:August 2010
End Date:April 2011

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A Multi-Center, Primary Care-Based, Open-Label Study to Assess the Success of Converting Opioid-Experienced Patients, With Chronic, Moderate to Severe Pain, to EMBEDA Using a Standardized Conversion Guide, and to Identify Behaviors Related to Prescription Opioid Abuse, Misuse, and Diversion

The purpose of the research study is to find out if opioid dependent chronic pain patients
who are judged by their physician to be eligible to change their current opioid medicine and
to participate in this study can be successfully adjusted to a stable dose of EMBEDA
(morphine sulfate and naltrexone hydrochloride). The study will also assess each patient's
risk for prescription opioid abuse, misuse and diversion.

The decision to terminate the trial was based on a lack of study drug supply. The decision
was not based on any safety concerns. The termination letter was sent on 11March2011.

Inclusion Criteria:

- Be able to read, speak and understand English

- Have chronic moderate to severe pain for at least 3 months

- Require around the clock opioid medication for the relief of pain

- Have been taking a daily opioid for at least 30 days prior to starting the study

- Be able to be safely switched to a different pain medication

- Be practicing acceptable birth control methods for female patients of childbearing
potential

- Be willing to participate in the study and able to comply with study procedures

Exclusion Criteria:

- Be currently diagnosed with or participating in and/or seeking treatment for opioid
and/or alcohol abuse

- Be allergic or intolerant to morphine, morphine salts, naltrexone or other opioids

- Be currently taking tramadol and/or extended release morphine products

- Have respiratory depression

- Have acute or severe bronchial asthma or severe chronic obstructive pulmonary disease

- Have migraines as your main source of pain

- Have any form of bowel obstruction

- Be pregnant or breast feeding

- Have had 2 or more surgeries for low back pain

- Be planning a major surgery during the study

- Be staying in a hospital or nursing home

- Be planning to have steroid injections for your chronic pain during the study

- Have a life expectancy of less than 2 months
We found this trial at
164
sites
391 Southcrest Parkway
Southhaven, Mississippi 38671
1874
mi
from 98109
Southhaven, MS
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1044 SW 44th Street
Oklahoma City, Oklahoma 73109
405-616-4888
1525
mi
from 98109
Oklahoma City, OK
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11045 N. 19th Avenue
Phoenix, Arizona 85029
602-395-1200
1107
mi
from 98109
Phoenix, AZ
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4820 Park Blvd N.
Pinellas Park, Florida 33781
2521
mi
from 98109
Pinellas Park, FL
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3212 Cove Bend Drive
Tampa, Florida 33613
2522
mi
from 98109
Tampa, FL
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3915 Veterans Memorial Drive
Adamsville, Alabama 35005
2070
mi
from 98109
Adamsville, AL
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451 West Chew Street
Allentown, Pennsylvania 18102
2337
mi
from 98109
Allentown, PA
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604 East Park Avenue
Anaconda, Montana 59711
455
mi
from 98109
Anaconda, MT
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Anderson, South Carolina 29621
2227
mi
from 98109
Anderson, SC
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5720 Fayetteville Road
Asheboro, North Carolina 27203
2343
mi
from 98109
Asheboro, NC
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400 Cherry Tree Road
Aston, Pennsylvania 19014
2364
mi
from 98109
Aston, PA
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Atco, New Jersey 08004
2392
mi
from 98109
Atco, NJ
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2173
mi
from 98109
Atlanta, GA
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Aurora, Colorado 80012
1028
mi
from 98109
Aurora, CO
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526 Water Street
Belvidere, New Jersey 07823
2348
mi
from 98109
Belvidere, NJ
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180 Debuys Road
Biloxi, Mississippi 39531
2124
mi
from 98109
Biloxi, MS
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2229 Cahaba Valley Drive
Birmingham, Alabama 35209
2089
mi
from 98109
Birmingham, AL
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Bountiful, Utah 84010
695
mi
from 98109
Bountiful, UT
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Boynton Beach, Florida 33472
2701
mi
from 98109
Boynton Beach, FL
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Brockton, Massachusetts 02301
2495
mi
from 98109
Brockton, MA
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Carlisle, Ohio 45005
1961
mi
from 98109
Carlisle, OH
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Centerville, Ohio 45459
1964
mi
from 98109
Centerville, OH
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Charleston, South Carolina 29406
2423
mi
from 98109
Charleston, SC
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Charleston, South Carolina 29412
2424
mi
from 98109
Charleston, SC
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Charlotte, North Carolina 28204
2282
mi
from 98109
Charlotte, NC
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Chattanooga, Tennessee 37404
2085
mi
from 98109
Chattanooga, TN
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1733
mi
from 98109
Chicago, IL
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Cincinnati, Ohio 45224
1962
mi
from 98109
Cincinnati, OH
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1967
mi
from 98109
Cincinnati, OH
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Clarkston, Michigan
1904
mi
from 98109
Clarkston, MI
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Clearwater, Florida 33755
2511
mi
from 98109
Clearwater, FL
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College Park, Maryland 20740
2324
mi
from 98109
College Park, MD
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Colorado Springs, Colorado 80904
1067
mi
from 98109
Colorado Springs, CO
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?
mi
from 98109
Columbus, GA
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Corsicana, Texas 75110
1729
mi
from 98109
Corsicana, TX
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Costa Mesa, California 92626
991
mi
from 98109
Costa Mesa, CA
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120 Wagner Drive
Creve Coeur, Illinois 61610
1679
mi
from 98109
Creve Coeur, IL
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1680
mi
from 98109
Dallas, TX
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2534
mi
from 98109
Debary, FL
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3290 Memorial Drive
Decatur, Georgia 30032
2184
mi
from 98109
Decatur, GA
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6 Lexington Boulevard
Delaware, Ohio 43015
1992
mi
from 98109
Delaware, OH
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Duncansville, Pennsylvania 16635
2206
mi
from 98109
Duncansville, PA
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11707 North Williams Street
Dunnellon, Florida 34432
2475
mi
from 98109
Dunnellon, FL
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Edina, Minnesota 55435
1390
mi
from 98109
Edina, MN
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Edmonds, Washington 98026
12
mi
from 98109
Edmonds, WA
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El Paso, Texas 79902
1375
mi
from 98109
El Paso, TX
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Elizabeth, New Jersey 07202
2394
mi
from 98109
Elizabeth, NJ
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Fall River, Massachusetts 02720
2501
mi
from 98109
Fall River, MA
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Flint, Michigan 48504
1880
mi
from 98109
Flint, MI
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3499 Linden Road
Flint, Michigan 48507
1881
mi
from 98109
Flint, MI
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Florissant, Missouri 63031
1709
mi
from 98109
Florissant, MO
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Florissant, Missouri 63033
1709
mi
from 98109
Florissant, MO
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Foothill Ranch, California 92610
920
mi
from 98109
Foothill Ranch, CA
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Fort Collins, Colorado 80525
981
mi
from 98109
Fort Collins, CO
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300 Business Parkway
Franklin, Ohio 45005
1960
mi
from 98109
Franklin, OH
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11 Murray Street
Glens Falls, New York 12801
2338
mi
from 98109
Glens Falls, NY
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Goodyear, Arizona 85395
1106
mi
from 98109
Goodyear, AZ
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2412
mi
from 98109
Great Neck, NY
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2755 South Carolina 14
Greer, South Carolina 29650
2232
mi
from 98109
Greer, SC
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Hackensack, New Jersey 76010
1672
mi
from 98109
Hackensack, NJ
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Haddon Heights, New Jersey 08035
2380
mi
from 98109
Haddon Heights, NJ
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Harrisburg, Pennsylvania 17112
2285
mi
from 98109
Harrisburg, PA
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Hartsdale, New York 10530
2402
mi
from 98109
Hartsdale, NY
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Hendersonville, Tennessee 37075
1972
mi
from 98109
Hendersonville, TN
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2722
mi
from 98109
Hialeah, FL
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Hialeah, Florida 33012
2722
mi
from 98109
Hialeah, FL
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1771 Tate Boulevard Southeast
Hickory, North Carolina 28602
2240
mi
from 98109
Hickory, NC
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2110 Higdon Ferry Road
Hot Springs, Arkansas 71913
1760
mi
from 98109
Hot Springs, AR
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3400 Bissonnet Street
Houston, Texas 77005
1889
mi
from 98109
Houston, TX
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1890
mi
from 98109
Houston, TX
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14629 Beechnut Street
Houston, Texas 77083
1883
mi
from 98109
Houston, TX
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1623 13th Avenue
Huntington, West Virginia 25701
2088
mi
from 98109
Huntington, WV
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Huntsville, Alabama 35801
2039
mi
from 98109
Huntsville, AL
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201 Governors Drive Southeast
Huntsville, Alabama 35801
2038
mi
from 98109
Huntsville, AL
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Indianapolis, Indiana 46256
1870
mi
from 98109
Indianapolis, IN
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Inglewood, California
967
mi
from 98109
Inglewood, CA
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Jackson, Mississippi 39202
1983
mi
from 98109
Jackson, MS
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Jacksonville, North Carolina 28546
2458
mi
from 98109
Jacksonville, NC
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2709 Industrial Drive
Jefferson City, Missouri 65109
1629
mi
from 98109
Jefferson City, MO
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Jonesboro, Arkansas 72401
1806
mi
from 98109
Jonesboro, AR
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Kissimmee, Florida 34741
2556
mi
from 98109
Kissimmee, FL
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La Mesa, California 91942
1063
mi
from 98109
La Mesa, CA
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Laguna Hills, California 92637
999
mi
from 98109
Laguna Hills, CA
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Lake Oswego, Oregon 97035
153
mi
from 98109
Lake Oswego, OR
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2147 Northeast Coachman Road
Lakeland, Florida 33810
2513
mi
from 98109
Lakeland, FL
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Lansing, Michigan 48917
1848
mi
from 98109
Lansing, MI
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Lexington, Kentucky 40503
2004
mi
from 98109
Lexington, KY
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Linden, New Jersey 07036
2393
mi
from 98109
Linden, NJ
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979
mi
from 98109
Long Beach, CA
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305 Laurelton Boulevard
Long Beach, New York 11561
2421
mi
from 98109
Long Beach, NY
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Los Angeles, California 90017
961
mi
from 98109
Los Angeles, CA
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Los Gatos, California 95032
719
mi
from 98109
Los Gatos, CA
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3012 Eastpoint Parkway
Louisville, Kentucky 40223
1949
mi
from 98109
Louisville, KY
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515 Middle Turnpike West
Manchester, Connecticut 06040
2435
mi
from 98109
Manchester, CT
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Mayville, New York 14757
2101
mi
from 98109
Mayville, NY
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Miami, Florida 33155
2728
mi
from 98109
Miami, FL
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Miami, Florida 33175
2732
mi
from 98109
Miami, FL
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Miami Beach, Florida 33140
2732
mi
from 98109
Miami Beach, FL
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1773
mi
from 98109
Michigan City, IN
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234 Broad Street
Milford, Connecticut 06460
2429
mi
from 98109
Milford, CT
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15550 Southeast McLoughlin Boulevard
Milwaukie, Oregon 97222
154
mi
from 98109
Milwaukie, OR
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