Conversion to Embeda With Rescue Trial



Status:Terminated
Conditions:Chronic Pain
Therapuetic Areas:Musculoskeletal
Healthy:No
Age Range:21 - Any
Updated:10/14/2017
Start Date:August 2010
End Date:April 2011

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A Multi-Center, Primary Care-Based, Open-Label Study to Assess the Success of Converting Opioid-Experienced Patients, With Chronic, Moderate to Severe Pain, to EMBEDA Using a Standardized Conversion Guide, and to Identify Behaviors Related to Prescription Opioid Abuse, Misuse, and Diversion

The purpose of the research study is to find out if opioid dependent chronic pain patients
who are judged by their physician to be eligible to change their current opioid medicine and
to participate in this study can be successfully adjusted to a stable dose of EMBEDA
(morphine sulfate and naltrexone hydrochloride). The study will also assess each patient's
risk for prescription opioid abuse, misuse and diversion.

The decision to terminate the trial was based on a lack of study drug supply. The decision
was not based on any safety concerns. The termination letter was sent on 11March2011.

Inclusion Criteria:

- Be able to read, speak and understand English

- Have chronic moderate to severe pain for at least 3 months

- Require around the clock opioid medication for the relief of pain

- Have been taking a daily opioid for at least 30 days prior to starting the study

- Be able to be safely switched to a different pain medication

- Be practicing acceptable birth control methods for female patients of childbearing
potential

- Be willing to participate in the study and able to comply with study procedures

Exclusion Criteria:

- Be currently diagnosed with or participating in and/or seeking treatment for opioid
and/or alcohol abuse

- Be allergic or intolerant to morphine, morphine salts, naltrexone or other opioids

- Be currently taking tramadol and/or extended release morphine products

- Have respiratory depression

- Have acute or severe bronchial asthma or severe chronic obstructive pulmonary disease

- Have migraines as your main source of pain

- Have any form of bowel obstruction

- Be pregnant or breast feeding

- Have had 2 or more surgeries for low back pain

- Be planning a major surgery during the study

- Be staying in a hospital or nursing home

- Be planning to have steroid injections for your chronic pain during the study

- Have a life expectancy of less than 2 months
We found this trial at
164
sites
391 Southcrest Parkway
Southhaven, Mississippi 38671
475
mi
from
Southhaven, MS
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1044 SW 44th Street
Oklahoma City, Oklahoma 73109
405-616-4888
161
mi
from
Oklahoma City, OK
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11045 N. 19th Avenue
Phoenix, Arizona 85029
602-395-1200
850
mi
from
Phoenix, AZ
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4820 Park Blvd N.
Pinellas Park, Florida 33781
1111
mi
from
Pinellas Park, FL
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3212 Cove Bend Drive
Tampa, Florida 33613
1112
mi
from
Tampa, FL
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3915 Veterans Memorial Drive
Adamsville, Alabama 35005
674
mi
from
Adamsville, AL
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451 West Chew Street
Allentown, Pennsylvania 18102
1209
mi
from
Allentown, PA
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604 East Park Avenue
Anaconda, Montana 59711
966
mi
from
Anaconda, MT
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Anderson, South Carolina 29621
875
mi
from
Anderson, SC
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5720 Fayetteville Road
Asheboro, North Carolina 27203
1050
mi
from
Asheboro, NC
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400 Cherry Tree Road
Aston, Pennsylvania 19014
1210
mi
from
Aston, PA
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Atco, New Jersey 08004
1239
mi
from
Atco, NJ
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799
mi
from
Atlanta, GA
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Aurora, Colorado 80012
401
mi
from
Aurora, CO
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526 Water Street
Belvidere, New Jersey 07823
1231
mi
from
Belvidere, NJ
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180 Debuys Road
Biloxi, Mississippi 39531
715
mi
from
Biloxi, MS
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2229 Cahaba Valley Drive
Birmingham, Alabama 35209
693
mi
from
Birmingham, AL
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Bountiful, Utah 84010
780
mi
from
Bountiful, UT
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Boynton Beach, Florida 33472
1292
mi
from
Boynton Beach, FL
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Brockton, Massachusetts 02301
1445
mi
from
Brockton, MA
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Carlisle, Ohio 45005
738
mi
from
Carlisle, OH
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Centerville, Ohio 45459
746
mi
from
Centerville, OH
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Charleston, South Carolina 29406
1063
mi
from
Charleston, SC
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Charleston, South Carolina 29412
1064
mi
from
Charleston, SC
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Charlotte, North Carolina 28204
958
mi
from
Charlotte, NC
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Chattanooga, Tennessee 37404
722
mi
from
Chattanooga, TN
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609
mi
from
Chicago, IL
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Cincinnati, Ohio 45224
724
mi
from
Cincinnati, OH
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726
mi
from
Cincinnati, OH
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Clarkston, Michigan
832
mi
from
Clarkston, MI
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Clearwater, Florida 33755
1100
mi
from
Clearwater, FL
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College Park, Maryland 20740
1132
mi
from
College Park, MD
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Colorado Springs, Colorado 80904
386
mi
from
Colorado Springs, CO
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?
mi
from
Columbus, GA
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Corsicana, Texas 75110
399
mi
from
Corsicana, TX
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Costa Mesa, California 92626
1158
mi
from
Costa Mesa, CA
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120 Wagner Drive
Creve Coeur, Illinois 61610
483
mi
from
Creve Coeur, IL
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347
mi
from
Dallas, TX
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1130
mi
from
Debary, FL
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3290 Memorial Drive
Decatur, Georgia 30032
807
mi
from
Decatur, GA
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6 Lexington Boulevard
Delaware, Ohio 43015
808
mi
from
Delaware, OH
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Duncansville, Pennsylvania 16635
1053
mi
from
Duncansville, PA
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11707 North Williams Street
Dunnellon, Florida 34432
1068
mi
from
Dunnellon, FL
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Edina, Minnesota 55435
544
mi
from
Edina, MN
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Edmonds, Washington 98026
1417
mi
from
Edmonds, WA
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El Paso, Texas 79902
641
mi
from
El Paso, TX
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Elizabeth, New Jersey 07202
1275
mi
from
Elizabeth, NJ
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Fall River, Massachusetts 02720
1437
mi
from
Fall River, MA
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Flint, Michigan 48504
824
mi
from
Flint, MI
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3499 Linden Road
Flint, Michigan 48507
821
mi
from
Flint, MI
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Florissant, Missouri 63031
412
mi
from
Florissant, MO
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Florissant, Missouri 63033
412
mi
from
Florissant, MO
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Foothill Ranch, California 92610
1160
mi
from
Foothill Ranch, CA
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Fort Collins, Colorado 80525
435
mi
from
Fort Collins, CO
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300 Business Parkway
Franklin, Ohio 45005
738
mi
from
Franklin, OH
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11 Murray Street
Glens Falls, New York 12801
1320
mi
from
Glens Falls, NY
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Goodyear, Arizona 85395
868
mi
from
Goodyear, AZ
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1301
mi
from
Great Neck, NY
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2755 South Carolina 14
Greer, South Carolina 29650
890
mi
from
Greer, SC
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Hackensack, New Jersey 76010
349
mi
from
Hackensack, NJ
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Haddon Heights, New Jersey 08035
1230
mi
from
Haddon Heights, NJ
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Harrisburg, Pennsylvania 17112
1140
mi
from
Harrisburg, PA
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Hartsdale, New York 10530
1298
mi
from
Hartsdale, NY
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Hendersonville, Tennessee 37075
625
mi
from
Hendersonville, TN
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1312
mi
from
Hialeah, FL
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Hialeah, Florida 33012
1312
mi
from
Hialeah, FL
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1771 Tate Boulevard Southeast
Hickory, North Carolina 28602
923
mi
from
Hickory, NC
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2110 Higdon Ferry Road
Hot Springs, Arkansas 71913
349
mi
from
Hot Springs, AR
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3400 Bissonnet Street
Houston, Texas 77005
571
mi
from
Houston, TX
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569
mi
from
Houston, TX
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14629 Beechnut Street
Houston, Texas 77083
570
mi
from
Houston, TX
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1623 13th Avenue
Huntington, West Virginia 25701
837
mi
from
Huntington, WV
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Huntsville, Alabama 35801
661
mi
from
Huntsville, AL
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201 Governors Drive Southeast
Huntsville, Alabama 35801
659
mi
from
Huntsville, AL
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Indianapolis, Indiana 46256
652
mi
from
Indianapolis, IN
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Inglewood, California
1176
mi
from
Inglewood, CA
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Jackson, Mississippi 39202
572
mi
from
Jackson, MS
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Jacksonville, North Carolina 28546
1152
mi
from
Jacksonville, NC
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2709 Industrial Drive
Jefferson City, Missouri 65109
309
mi
from
Jefferson City, MO
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Jonesboro, Arkansas 72401
416
mi
from
Jonesboro, AR
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Kissimmee, Florida 34741
1149
mi
from
Kissimmee, FL
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La Mesa, California 91942
1133
mi
from
La Mesa, CA
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Laguna Hills, California 92637
1148
mi
from
Laguna Hills, CA
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Lake Oswego, Oregon 97035
1382
mi
from
Lake Oswego, OR
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2147 Northeast Coachman Road
Lakeland, Florida 33810
1102
mi
from
Lakeland, FL
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Lansing, Michigan 48917
774
mi
from
Lansing, MI
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Lexington, Kentucky 40503
724
mi
from
Lexington, KY
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Linden, New Jersey 07036
1274
mi
from
Linden, NJ
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1171
mi
from
Long Beach, CA
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305 Laurelton Boulevard
Long Beach, New York 11561
1304
mi
from
Long Beach, NY
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Los Angeles, California 90017
1169
mi
from
Los Angeles, CA
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Los Gatos, California 95032
1321
mi
from
Los Gatos, CA
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3012 Eastpoint Parkway
Louisville, Kentucky 40223
670
mi
from
Louisville, KY
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515 Middle Turnpike West
Manchester, Connecticut 06040
1365
mi
from
Manchester, CT
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Mayville, New York 14757
1016
mi
from
Mayville, NY
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Miami, Florida 33155
1317
mi
from
Miami, FL
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Miami, Florida 33175
1321
mi
from
Miami, FL
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Miami Beach, Florida 33140
1322
mi
from
Miami Beach, FL
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641
mi
from
Michigan City, IN
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234 Broad Street
Milford, Connecticut 06460
1337
mi
from
Milford, CT
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15550 Southeast McLoughlin Boulevard
Milwaukie, Oregon 97222
1379
mi
from
Milwaukie, OR
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