Conversion to Embeda With Rescue Trial



Status:Terminated
Conditions:Chronic Pain
Therapuetic Areas:Musculoskeletal
Healthy:No
Age Range:21 - Any
Updated:10/14/2017
Start Date:August 2010
End Date:April 2011

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A Multi-Center, Primary Care-Based, Open-Label Study to Assess the Success of Converting Opioid-Experienced Patients, With Chronic, Moderate to Severe Pain, to EMBEDA Using a Standardized Conversion Guide, and to Identify Behaviors Related to Prescription Opioid Abuse, Misuse, and Diversion

The purpose of the research study is to find out if opioid dependent chronic pain patients
who are judged by their physician to be eligible to change their current opioid medicine and
to participate in this study can be successfully adjusted to a stable dose of EMBEDA
(morphine sulfate and naltrexone hydrochloride). The study will also assess each patient's
risk for prescription opioid abuse, misuse and diversion.

The decision to terminate the trial was based on a lack of study drug supply. The decision
was not based on any safety concerns. The termination letter was sent on 11March2011.

Inclusion Criteria:

- Be able to read, speak and understand English

- Have chronic moderate to severe pain for at least 3 months

- Require around the clock opioid medication for the relief of pain

- Have been taking a daily opioid for at least 30 days prior to starting the study

- Be able to be safely switched to a different pain medication

- Be practicing acceptable birth control methods for female patients of childbearing
potential

- Be willing to participate in the study and able to comply with study procedures

Exclusion Criteria:

- Be currently diagnosed with or participating in and/or seeking treatment for opioid
and/or alcohol abuse

- Be allergic or intolerant to morphine, morphine salts, naltrexone or other opioids

- Be currently taking tramadol and/or extended release morphine products

- Have respiratory depression

- Have acute or severe bronchial asthma or severe chronic obstructive pulmonary disease

- Have migraines as your main source of pain

- Have any form of bowel obstruction

- Be pregnant or breast feeding

- Have had 2 or more surgeries for low back pain

- Be planning a major surgery during the study

- Be staying in a hospital or nursing home

- Be planning to have steroid injections for your chronic pain during the study

- Have a life expectancy of less than 2 months
We found this trial at
164
sites
526 Water Street
Belvidere, New Jersey 07823
230
mi
from 02139
Belvidere, NJ
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1044 SW 44th Street
Oklahoma City, Oklahoma 73109
405-616-4888
1492
mi
from 02139
Oklahoma City, OK
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11045 N. 19th Avenue
Phoenix, Arizona 85029
602-395-1200
2289
mi
from 02139
Phoenix, AZ
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4820 Park Blvd N.
Pinellas Park, Florida 33781
1196
mi
from 02139
Pinellas Park, FL
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3212 Cove Bend Drive
Tampa, Florida 33613
1173
mi
from 02139
Tampa, FL
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3915 Veterans Memorial Drive
Adamsville, Alabama 35005
1051
mi
from 02139
Adamsville, AL
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451 West Chew Street
Allentown, Pennsylvania 18102
256
mi
from 02139
Allentown, PA
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604 East Park Avenue
Anaconda, Montana 59711
2062
mi
from 02139
Anaconda, MT
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Anderson, South Carolina 29621
824
mi
from 02139
Anderson, SC
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5720 Fayetteville Road
Asheboro, North Carolina 27203
610
mi
from 02139
Asheboro, NC
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400 Cherry Tree Road
Aston, Pennsylvania 19014
284
mi
from 02139
Aston, PA
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Atco, New Jersey 08004
266
mi
from 02139
Atco, NJ
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922
mi
from 02139
Atlanta, GA
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Aurora, Colorado 80012
1756
mi
from 02139
Aurora, CO
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180 Debuys Road
Biloxi, Mississippi 39531
1289
mi
from 02139
Biloxi, MS
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2229 Cahaba Valley Drive
Birmingham, Alabama 35209
1047
mi
from 02139
Birmingham, AL
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Bountiful, Utah 84010
2088
mi
from 02139
Bountiful, UT
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Boynton Beach, Florida 33472
1205
mi
from 02139
Boynton Beach, FL
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Brockton, Massachusetts 02301
19
mi
from 02139
Brockton, MA
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Carlisle, Ohio 45005
715
mi
from 02139
Carlisle, OH
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Centerville, Ohio 45459
705
mi
from 02139
Centerville, OH
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Charleston, South Carolina 29406
818
mi
from 02139
Charleston, SC
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Charleston, South Carolina 29412
822
mi
from 02139
Charleston, SC
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Charlotte, North Carolina 28204
719
mi
from 02139
Charlotte, NC
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Chattanooga, Tennessee 37404
915
mi
from 02139
Chattanooga, TN
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847
mi
from 02139
Chicago, IL
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Cincinnati, Ohio 45224
734
mi
from 02139
Cincinnati, OH
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735
mi
from 02139
Cincinnati, OH
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Clarkston, Michigan
626
mi
from 02139
Clarkston, MI
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Clearwater, Florida 33755
1190
mi
from 02139
Clearwater, FL
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College Park, Maryland 20740
384
mi
from 02139
College Park, MD
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Colorado Springs, Colorado 80904
1773
mi
from 02139
Colorado Springs, CO
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?
mi
from 02139
Columbus, GA
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Corsicana, Texas 75110
1556
mi
from 02139
Corsicana, TX
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Costa Mesa, California 92626
2583
mi
from 02139
Costa Mesa, CA
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120 Wagner Drive
Creve Coeur, Illinois 61610
962
mi
from 02139
Creve Coeur, IL
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1547
mi
from 02139
Dallas, TX
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1092
mi
from 02139
Debary, FL
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3290 Memorial Drive
Decatur, Georgia 30032
929
mi
from 02139
Decatur, GA
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6 Lexington Boulevard
Delaware, Ohio 43015
637
mi
from 02139
Delaware, OH
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Duncansville, Pennsylvania 16635
402
mi
from 02139
Duncansville, PA
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11707 North Williams Street
Dunnellon, Florida 34432
1116
mi
from 02139
Dunnellon, FL
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Edina, Minnesota 55435
1121
mi
from 02139
Edina, MN
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Edmonds, Washington 98026
2482
mi
from 02139
Edmonds, WA
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El Paso, Texas 79902
2065
mi
from 02139
El Paso, TX
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Elizabeth, New Jersey 07202
199
mi
from 02139
Elizabeth, NJ
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Fall River, Massachusetts 02720
44
mi
from 02139
Fall River, MA
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Flint, Michigan 48504
643
mi
from 02139
Flint, MI
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3499 Linden Road
Flint, Michigan 48507
644
mi
from 02139
Flint, MI
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Florissant, Missouri 63031
1035
mi
from 02139
Florissant, MO
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Florissant, Missouri 63033
1035
mi
from 02139
Florissant, MO
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Foothill Ranch, California 92610
2574
mi
from 02139
Foothill Ranch, CA
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Fort Collins, Colorado 80525
1751
mi
from 02139
Fort Collins, CO
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300 Business Parkway
Franklin, Ohio 45005
714
mi
from 02139
Franklin, OH
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11 Murray Street
Glens Falls, New York 12801
144
mi
from 02139
Glens Falls, NY
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Goodyear, Arizona 85395
2308
mi
from 02139
Goodyear, AZ
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173
mi
from 02139
Great Neck, NY
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2755 South Carolina 14
Greer, South Carolina 29650
791
mi
from 02139
Greer, SC
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Hackensack, New Jersey 76010
1562
mi
from 02139
Hackensack, NJ
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Haddon Heights, New Jersey 08035
268
mi
from 02139
Haddon Heights, NJ
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Harrisburg, Pennsylvania 17112
325
mi
from 02139
Harrisburg, PA
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Hartsdale, New York 10530
167
mi
from 02139
Hartsdale, NY
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Hendersonville, Tennessee 37075
926
mi
from 02139
Hendersonville, TN
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1253
mi
from 02139
Hialeah, FL
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Hialeah, Florida 33012
1253
mi
from 02139
Hialeah, FL
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1771 Tate Boulevard Southeast
Hickory, North Carolina 28602
713
mi
from 02139
Hickory, NC
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2110 Higdon Ferry Road
Hot Springs, Arkansas 71913
1304
mi
from 02139
Hot Springs, AR
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3400 Bissonnet Street
Houston, Texas 77005
1606
mi
from 02139
Houston, TX
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1601
mi
from 02139
Houston, TX
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14629 Beechnut Street
Houston, Texas 77083
1617
mi
from 02139
Houston, TX
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1623 13th Avenue
Huntington, West Virginia 25701
654
mi
from 02139
Huntington, WV
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Huntsville, Alabama 35801
984
mi
from 02139
Huntsville, AL
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201 Governors Drive Southeast
Huntsville, Alabama 35801
986
mi
from 02139
Huntsville, AL
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Indianapolis, Indiana 46256
793
mi
from 02139
Indianapolis, IN
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Inglewood, California
2597
mi
from 02139
Inglewood, CA
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Jackson, Mississippi 39202
1252
mi
from 02139
Jackson, MS
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Jacksonville, North Carolina 28546
626
mi
from 02139
Jacksonville, NC
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2709 Industrial Drive
Jefferson City, Missouri 65109
1136
mi
from 02139
Jefferson City, MO
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Jonesboro, Arkansas 72401
1138
mi
from 02139
Jonesboro, AR
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Kissimmee, Florida 34741
1130
mi
from 02139
Kissimmee, FL
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La Mesa, California 91942
2566
mi
from 02139
La Mesa, CA
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Laguna Hills, California 92637
2574
mi
from 02139
Laguna Hills, CA
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Lake Oswego, Oregon 97035
2531
mi
from 02139
Lake Oswego, OR
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2147 Northeast Coachman Road
Lakeland, Florida 33810
1189
mi
from 02139
Lakeland, FL
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Lansing, Michigan 48917
688
mi
from 02139
Lansing, MI
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Lexington, Kentucky 40503
769
mi
from 02139
Lexington, KY
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Linden, New Jersey 07036
202
mi
from 02139
Linden, NJ
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2593
mi
from 02139
Long Beach, CA
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305 Laurelton Boulevard
Long Beach, New York 11561
181
mi
from 02139
Long Beach, NY
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Los Angeles, California 90017
2589
mi
from 02139
Los Angeles, CA
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Los Gatos, California 95032
2683
mi
from 02139
Los Gatos, CA
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3012 Eastpoint Parkway
Louisville, Kentucky 40223
808
mi
from 02139
Louisville, KY
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515 Middle Turnpike West
Manchester, Connecticut 06040
84
mi
from 02139
Manchester, CT
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Mayville, New York 14757
428
mi
from 02139
Mayville, NY
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Miami, Florida 33155
1261
mi
from 02139
Miami, FL
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Miami, Florida 33175
1260
mi
from 02139
Miami, FL
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Miami Beach, Florida 33140
1252
mi
from 02139
Miami Beach, FL
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809
mi
from 02139
Michigan City, IN
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234 Broad Street
Milford, Connecticut 06460
128
mi
from 02139
Milford, CT
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15550 Southeast McLoughlin Boulevard
Milwaukie, Oregon 97222
2530
mi
from 02139
Milwaukie, OR
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524 East McKinley Avenue
Mishawaka, Indiana 46545
774
mi
from 02139
Mishawaka, IN
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