Conversion to Embeda With Rescue Trial



Status:Terminated
Conditions:Chronic Pain
Therapuetic Areas:Musculoskeletal
Healthy:No
Age Range:21 - Any
Updated:10/14/2017
Start Date:August 2010
End Date:April 2011

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A Multi-Center, Primary Care-Based, Open-Label Study to Assess the Success of Converting Opioid-Experienced Patients, With Chronic, Moderate to Severe Pain, to EMBEDA Using a Standardized Conversion Guide, and to Identify Behaviors Related to Prescription Opioid Abuse, Misuse, and Diversion

The purpose of the research study is to find out if opioid dependent chronic pain patients
who are judged by their physician to be eligible to change their current opioid medicine and
to participate in this study can be successfully adjusted to a stable dose of EMBEDA
(morphine sulfate and naltrexone hydrochloride). The study will also assess each patient's
risk for prescription opioid abuse, misuse and diversion.

The decision to terminate the trial was based on a lack of study drug supply. The decision
was not based on any safety concerns. The termination letter was sent on 11March2011.

Inclusion Criteria:

- Be able to read, speak and understand English

- Have chronic moderate to severe pain for at least 3 months

- Require around the clock opioid medication for the relief of pain

- Have been taking a daily opioid for at least 30 days prior to starting the study

- Be able to be safely switched to a different pain medication

- Be practicing acceptable birth control methods for female patients of childbearing
potential

- Be willing to participate in the study and able to comply with study procedures

Exclusion Criteria:

- Be currently diagnosed with or participating in and/or seeking treatment for opioid
and/or alcohol abuse

- Be allergic or intolerant to morphine, morphine salts, naltrexone or other opioids

- Be currently taking tramadol and/or extended release morphine products

- Have respiratory depression

- Have acute or severe bronchial asthma or severe chronic obstructive pulmonary disease

- Have migraines as your main source of pain

- Have any form of bowel obstruction

- Be pregnant or breast feeding

- Have had 2 or more surgeries for low back pain

- Be planning a major surgery during the study

- Be staying in a hospital or nursing home

- Be planning to have steroid injections for your chronic pain during the study

- Have a life expectancy of less than 2 months
We found this trial at
164
sites
793 Cook Road
Orangeburg, South Carolina 29118
460
mi
from 43215
Orangeburg, SC
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1044 SW 44th Street
Oklahoma City, Oklahoma 73109
405-616-4888
851
mi
from 43215
Oklahoma City, OK
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11045 N. 19th Avenue
Phoenix, Arizona 85029
602-395-1200
1660
mi
from 43215
Phoenix, AZ
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4820 Park Blvd N.
Pinellas Park, Florida 33781
838
mi
from 43215
Pinellas Park, FL
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3212 Cove Bend Drive
Tampa, Florida 33613
821
mi
from 43215
Tampa, FL
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3915 Veterans Memorial Drive
Adamsville, Alabama 35005
490
mi
from 43215
Adamsville, AL
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451 West Chew Street
Allentown, Pennsylvania 18102
400
mi
from 43215
Allentown, PA
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604 East Park Avenue
Anaconda, Montana 59711
1559
mi
from 43215
Anaconda, MT
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Anderson, South Carolina 29621
376
mi
from 43215
Anderson, SC
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5720 Fayetteville Road
Asheboro, North Carolina 27203
357
mi
from 43215
Asheboro, NC
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400 Cherry Tree Road
Aston, Pennsylvania 19014
401
mi
from 43215
Aston, PA
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Atco, New Jersey 08004
431
mi
from 43215
Atco, NJ
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422
mi
from 43215
Atlanta, GA
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Aurora, Colorado 80012
1154
mi
from 43215
Aurora, CO
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526 Water Street
Belvidere, New Jersey 07823
422
mi
from 43215
Belvidere, NJ
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180 Debuys Road
Biloxi, Mississippi 39531
742
mi
from 43215
Biloxi, MS
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2229 Cahaba Valley Drive
Birmingham, Alabama 35209
495
mi
from 43215
Birmingham, AL
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Bountiful, Utah 84010
1512
mi
from 43215
Bountiful, UT
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Boynton Beach, Florida 33472
943
mi
from 43215
Boynton Beach, FL
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Brockton, Massachusetts 02301
642
mi
from 43215
Brockton, MA
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Carlisle, Ohio 45005
74
mi
from 43215
Carlisle, OH
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Centerville, Ohio 45459
64
mi
from 43215
Centerville, OH
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Charleston, South Carolina 29406
525
mi
from 43215
Charleston, SC
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Charleston, South Carolina 29412
527
mi
from 43215
Charleston, SC
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Charlotte, North Carolina 28204
349
mi
from 43215
Charlotte, NC
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Chattanooga, Tennessee 37404
362
mi
from 43215
Chattanooga, TN
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274
mi
from 43215
Chicago, IL
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Cincinnati, Ohio 45224
96
mi
from 43215
Cincinnati, OH
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98
mi
from 43215
Cincinnati, OH
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Clarkston, Michigan
192
mi
from 43215
Clarkston, MI
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Clearwater, Florida 33755
828
mi
from 43215
Clearwater, FL
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College Park, Maryland 20740
331
mi
from 43215
College Park, MD
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Colorado Springs, Colorado 80904
1163
mi
from 43215
Colorado Springs, CO
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?
mi
from 43215
Columbus, GA
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Corsicana, Texas 75110
925
mi
from 43215
Corsicana, TX
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Costa Mesa, California 92626
1964
mi
from 43215
Costa Mesa, CA
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120 Wagner Drive
Creve Coeur, Illinois 61610
349
mi
from 43215
Creve Coeur, IL
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911
mi
from 43215
Dallas, TX
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772
mi
from 43215
Debary, FL
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3290 Memorial Drive
Decatur, Georgia 30032
434
mi
from 43215
Decatur, GA
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6 Lexington Boulevard
Delaware, Ohio 43015
24
mi
from 43215
Delaware, OH
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Duncansville, Pennsylvania 16635
244
mi
from 43215
Duncansville, PA
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11707 North Williams Street
Dunnellon, Florida 34432
754
mi
from 43215
Dunnellon, FL
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Edina, Minnesota 55435
625
mi
from 43215
Edina, MN
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Edmonds, Washington 98026
2009
mi
from 43215
Edmonds, WA
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El Paso, Texas 79902
1424
mi
from 43215
El Paso, TX
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Elizabeth, New Jersey 07202
466
mi
from 43215
Elizabeth, NJ
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Fall River, Massachusetts 02720
632
mi
from 43215
Fall River, MA
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Flint, Michigan 48504
216
mi
from 43215
Flint, MI
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3499 Linden Road
Flint, Michigan 48507
211
mi
from 43215
Flint, MI
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Florissant, Missouri 63031
398
mi
from 43215
Florissant, MO
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Florissant, Missouri 63033
398
mi
from 43215
Florissant, MO
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Foothill Ranch, California 92610
1961
mi
from 43215
Foothill Ranch, CA
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Fort Collins, Colorado 80525
1160
mi
from 43215
Fort Collins, CO
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300 Business Parkway
Franklin, Ohio 45005
73
mi
from 43215
Franklin, OH
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11 Murray Street
Glens Falls, New York 12801
535
mi
from 43215
Glens Falls, NY
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Goodyear, Arizona 85395
1678
mi
from 43215
Goodyear, AZ
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492
mi
from 43215
Great Neck, NY
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2755 South Carolina 14
Greer, South Carolina 29650
355
mi
from 43215
Greer, SC
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Hackensack, New Jersey 76010
926
mi
from 43215
Hackensack, NJ
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Haddon Heights, New Jersey 08035
421
mi
from 43215
Haddon Heights, NJ
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Harrisburg, Pennsylvania 17112
330
mi
from 43215
Harrisburg, PA
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Hartsdale, New York 10530
489
mi
from 43215
Hartsdale, NY
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Hendersonville, Tennessee 37075
319
mi
from 43215
Hendersonville, TN
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986
mi
from 43215
Hialeah, FL
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Hialeah, Florida 33012
986
mi
from 43215
Hialeah, FL
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1771 Tate Boulevard Southeast
Hickory, North Carolina 28602
307
mi
from 43215
Hickory, NC
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2110 Higdon Ferry Road
Hot Springs, Arkansas 71913
671
mi
from 43215
Hot Springs, AR
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3400 Bissonnet Street
Houston, Texas 77005
995
mi
from 43215
Houston, TX
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991
mi
from 43215
Houston, TX
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14629 Beechnut Street
Houston, Texas 77083
1006
mi
from 43215
Houston, TX
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1623 13th Avenue
Huntington, West Virginia 25701
112
mi
from 43215
Huntington, WV
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Huntsville, Alabama 35801
409
mi
from 43215
Huntsville, AL
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201 Governors Drive Southeast
Huntsville, Alabama 35801
411
mi
from 43215
Huntsville, AL
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Indianapolis, Indiana 46256
158
mi
from 43215
Indianapolis, IN
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Inglewood, California
1980
mi
from 43215
Inglewood, CA
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Jackson, Mississippi 39202
661
mi
from 43215
Jackson, MS
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Jacksonville, North Carolina 28546
473
mi
from 43215
Jacksonville, NC
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2709 Industrial Drive
Jefferson City, Missouri 65109
500
mi
from 43215
Jefferson City, MO
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Jonesboro, Arkansas 72401
505
mi
from 43215
Jonesboro, AR
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Kissimmee, Florida 34741
810
mi
from 43215
Kissimmee, FL
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La Mesa, California 91942
1942
mi
from 43215
La Mesa, CA
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Laguna Hills, California 92637
1954
mi
from 43215
Laguna Hills, CA
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Lake Oswego, Oregon 97035
2027
mi
from 43215
Lake Oswego, OR
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2147 Northeast Coachman Road
Lakeland, Florida 33810
828
mi
from 43215
Lakeland, FL
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Lansing, Michigan 48917
208
mi
from 43215
Lansing, MI
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Lexington, Kentucky 40503
157
mi
from 43215
Lexington, KY
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Linden, New Jersey 07036
464
mi
from 43215
Linden, NJ
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1975
mi
from 43215
Long Beach, CA
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305 Laurelton Boulevard
Long Beach, New York 11561
494
mi
from 43215
Long Beach, NY
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Los Angeles, California 90017
1973
mi
from 43215
Los Angeles, CA
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Los Gatos, California 95032
2095
mi
from 43215
Los Gatos, CA
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3012 Eastpoint Parkway
Louisville, Kentucky 40223
177
mi
from 43215
Louisville, KY
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515 Middle Turnpike West
Manchester, Connecticut 06040
561
mi
from 43215
Manchester, CT
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Mayville, New York 14757
241
mi
from 43215
Mayville, NY
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Miami, Florida 33155
995
mi
from 43215
Miami, FL
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Miami, Florida 33175
996
mi
from 43215
Miami, FL
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Miami Beach, Florida 33140
991
mi
from 43215
Miami Beach, FL
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234
mi
from 43215
Michigan City, IN
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234 Broad Street
Milford, Connecticut 06460
529
mi
from 43215
Milford, CT
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15550 Southeast McLoughlin Boulevard
Milwaukie, Oregon 97222
2024
mi
from 43215
Milwaukie, OR
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