Rubidium-82 Position Emission Computed Tomography (PET) Versus Gated, Rest / Stress Technetium 99-m SPECT
| Status: | Archived |
|---|---|
| Conditions: | Angina, Peripheral Vascular Disease, Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | January 2005 |
| End Date: | December 2011 |
A Prospective Comparison of Gated, Rest/Stress Rubidium-82 Position Emission Computed Tomography (PET) vs. Gated, Rest / Stress Technetium 99-m SPECT
Many stress tests being done today have two parts, the stress test and the pictures of your
heart. The investigators are comparing a newer technique to obtain the pictures (PET
imaging) to the standard method (SPECT imaging). However, it is not known if the new test
is better than the old test. It is important to have a standard to compare these tests to,
and that is why people who will be getting a cardiac catheterization are being asked to
participate. The information about your arteries from the cardiac catheterization will be
used to judge which stress test is better. The investigators hypothesize that the newer
method (PET imaging) will be more accurate than the old method (SPECT) in detecting heart
disease.
A SPECT rest image will be obtained using a technetium based isotope. On a separate day, a
Rubidium rest PET image will be obtained prior to a Dipyridamole stress test. Subjects will
receive both Rubidium and technetium isotopes following the Dipyridamole stress, and will
undergo first PET imaging and later SPECT imaging following the stress test. Patients will
then go for cardiac catheterization as clinically ordered by their physician.
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