Sex Differences in Attentional Bias in Marijuana-dependent Individuals



Status:Archived
Conditions:Psychiatric
Therapuetic Areas:Psychiatry / Psychology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:August 2009
End Date:December 2010

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Sex Differences in Attentional Bias and Cognitive Functioning in Response to Stress in Marijuana-dependent Individuals


The purpose of this study is to explore sex differences in cognitive functioning and
responses to marijuana-related items, and to determine whether stress impacts these
measures.

Hypothesis 1: Attentional bias will be greater for marijuana cues in male
marijuana-dependent subjects relative to female marijuana-dependent or non-dependent male
controls.

Hypothesis 2: Marijuana-dependent females will exhibit greater stress-induced changes in
attentional bias and cognitive functioning than marijuana-dependent males.


Ample evidence implicates both environmental cues and negative affective states in
maintaining drug use or triggering relapse. However, although 'craving' is believed to
drive continued drug use, it is not well understood how cognitive processes influence
craving and relapse, nor how they may differ between the sexes. Therefore, the goal of this
study protocol is to provide insight into sex differences in the cognitive aspects of drug
craving and to assess the impact of stress on attentional bias for drug-related cues as well
as on the availability of cognitive resources.


We found this trial at
1
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171 Ashley Avenue
Charleston, South Carolina 29425
843-792-1414
Medical University of South Carolina The Medical University of South Carolina (MUSC) has grown from...
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Charleston, SC
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