Prospective Observational Study of Peri-implantation Serum hCG Levels



Status:Completed
Conditions:Women's Studies, Infertility
Therapuetic Areas:Reproductive
Healthy:No
Age Range:Any
Updated:9/23/2012
Start Date:August 2010
End Date:August 2011
Contact:Bruce Shapiro, MD, PhD
Phone:(702) 254-1777

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The purpose of this study is to prospectively define a set of data suitable for developing
models of pregnancy viability. Those models will be based on serum hCG concentration
measured during the peri-implantation period in patients that received fresh embryo transfer
and those that received transfer of frozen-thawed embryos, and to compare and contrast these
models. This may reveal insights into differences between these types of IVF cycles.


The current study seeks to examine the effect of the timing of implantation (as indicated by
the first increase in serum hCG level) on the viability of pregnancies and to determine if
such effect of timing differs between fresh embryo transfers and frozen-thawed embryos
transfers. In this case, the timing of implantation will be measured through serum hCG
analysis on days 3, 4, 5, and 7 after blastocyst transfer.

Inclusion Criteria:

- IVF patients (adults) who received blastocyst transfer

Exclusion Criteria:

- Those patients using different laboratories
We found this trial at
1
site
Las Vegas, Nevada 89117
?
mi
from
Las Vegas, NV
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